The phenomenon of viral chromosomal integration
The literature review is devoted to the chromosomally integrating viruses, the integration property. These are revealed using modern diagnostic methods, including highthroughput sequencing. The review describes various types of viruses, such as retroviruses, adenoviruses, herpes viruses, papillomavi...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2024-09-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/1657 |
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| author | O. V. Goleva P. V. Cherkasova E. V. Baziian A. A. Igolkina Yu. A. Ejsmont N. V. Skripchenko A. B. Chukhlovin O. S. Glotov |
| author_facet | O. V. Goleva P. V. Cherkasova E. V. Baziian A. A. Igolkina Yu. A. Ejsmont N. V. Skripchenko A. B. Chukhlovin O. S. Glotov |
| author_sort | O. V. Goleva |
| collection | DOAJ |
| description | The literature review is devoted to the chromosomally integrating viruses, the integration property. These are revealed using modern diagnostic methods, including highthroughput sequencing. The review describes various types of viruses, such as retroviruses, adenoviruses, herpes viruses, papillomaviruses, hepatitis B, SARS-CoV-2 and others. These viruses have the ability to integrate their genomes into the host cell genomes and their prevalence. Modern information on the molecular mechanisms of viral integration and methods of differential diagnostics is presented. Each of these viruses has its own unique ways of interacting with the host cell genome to maintain a latent state, which determines the specifics of the infectious process and pathological consequences for the body due to the possibility of effective reactivation. |
| format | Article |
| id | doaj-art-3bc1d3cc664a412085f465782628dbf1 |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2024-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-3bc1d3cc664a412085f465782628dbf12025-08-20T03:38:30ZrusJournal InfectologyЖурнал инфектологии2072-67322024-09-0116351610.22625/2072-6732-2024-16-3-5-161157The phenomenon of viral chromosomal integrationO. V. Goleva0P. V. Cherkasova1E. V. Baziian2A. A. Igolkina3Yu. A. Ejsmont4N. V. Skripchenko5A. B. Chukhlovin6O. S. Glotov7Pediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious DiseasesPediatric Research and Clinical Center for Infectious Diseases; Saint-Petersburg State Pediatric Medical UniversityResearch Institute of Pediatric Oncology, Hematology and Transplantation named after R.M. Gorbacheva of First Saint-Petersburg State Medical University named after academician I.P. PavlovPediatric Research and Clinical Center for Infectious DiseasesThe literature review is devoted to the chromosomally integrating viruses, the integration property. These are revealed using modern diagnostic methods, including highthroughput sequencing. The review describes various types of viruses, such as retroviruses, adenoviruses, herpes viruses, papillomaviruses, hepatitis B, SARS-CoV-2 and others. These viruses have the ability to integrate their genomes into the host cell genomes and their prevalence. Modern information on the molecular mechanisms of viral integration and methods of differential diagnostics is presented. Each of these viruses has its own unique ways of interacting with the host cell genome to maintain a latent state, which determines the specifics of the infectious process and pathological consequences for the body due to the possibility of effective reactivation.https://journal.niidi.ru/jofin/article/view/1657viruseschromosomal integrationmechanismsdiagnostics |
| spellingShingle | O. V. Goleva P. V. Cherkasova E. V. Baziian A. A. Igolkina Yu. A. Ejsmont N. V. Skripchenko A. B. Chukhlovin O. S. Glotov The phenomenon of viral chromosomal integration Журнал инфектологии viruses chromosomal integration mechanisms diagnostics |
| title | The phenomenon of viral chromosomal integration |
| title_full | The phenomenon of viral chromosomal integration |
| title_fullStr | The phenomenon of viral chromosomal integration |
| title_full_unstemmed | The phenomenon of viral chromosomal integration |
| title_short | The phenomenon of viral chromosomal integration |
| title_sort | phenomenon of viral chromosomal integration |
| topic | viruses chromosomal integration mechanisms diagnostics |
| url | https://journal.niidi.ru/jofin/article/view/1657 |
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