Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score level

Abstract Background Improving the quality of medical care in hospitals is a major priority for all departments. The early warning score (EWS) trend is an effective early risk stratification tool that reflects the changes in patient condition and allows better assessment of deterioration risk. Object...

Full description

Saved in:
Bibliographic Details
Main Authors: Wen‐Chen Lin, Chin‐Fu Chang, Yan‐Ren Lin, Chih‐Wen Twu, Mei‐Chu Chen, Yu‐Pin Ku, Kang‐Ping Lin, Ching‐Hsiung Lin
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Hong Kong Journal of Emergency Medicine
Subjects:
Online Access:https://doi.org/10.1002/hkj2.12041
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850282558838800384
author Wen‐Chen Lin
Chin‐Fu Chang
Yan‐Ren Lin
Chih‐Wen Twu
Mei‐Chu Chen
Yu‐Pin Ku
Kang‐Ping Lin
Ching‐Hsiung Lin
author_facet Wen‐Chen Lin
Chin‐Fu Chang
Yan‐Ren Lin
Chih‐Wen Twu
Mei‐Chu Chen
Yu‐Pin Ku
Kang‐Ping Lin
Ching‐Hsiung Lin
author_sort Wen‐Chen Lin
collection DOAJ
description Abstract Background Improving the quality of medical care in hospitals is a major priority for all departments. The early warning score (EWS) trend is an effective early risk stratification tool that reflects the changes in patient condition and allows better assessment of deterioration risk. Objective The aim of this study was to investigate whether utilizing the trend of the modified early warning score (MEWS) level within 4 h of a patient's arrival in the emergency department (ED) could identify patients at risk of clinical deterioration at 8 h after arrival in the ED. Methods We conducted a retrospective observational study of non‐trauma patients who had at least two vital sign measurements (Glasgow Coma Scale score, heart rate, blood pressure, respiratory rate, and body temperature) within 8 h of arriving in the ED. The primary outcome was patients who had MEWS ≥ 4 at 8 h after arrival in the ED. We performed multivariate logistic regression analysis using age, sex, MEWS level at arrival in the ED, MEWS level within 4 h after arrival in the ED, and MEWS level trend over time. Results Among the 5825 patients, 680 (11.7%) were at risk of deterioration at 8 h after arrival in the ED. To predict the risk of deteriorating conditions (MEWS ≥ 4), utilizing the MEWS level trend within 4 h of arrival in the ED was more effective in identifying patients at risk of deterioration after 8 h of arrival in the ED compared to using a single MEWS value during the ED stay. The corresponding areas under the receiver operating characteristic curve were 0.756 (95% confidence interval (CI) 0.734–0.778) and 0.846 (95% CI 0.827–0.865), respectively (p < 0.01). Conclusions The proposed trend‐based predictive model for MEWS levels can alert healthcare personnel regarding patients at increased risk of deterioration (MEWS ≥ 4), potentially reducing mortality rates during ED stays.
format Article
id doaj-art-3bc1cfecaa794514947a724b3951b0dd
institution OA Journals
issn 1024-9079
2309-5407
language English
publishDate 2024-10-01
publisher Wiley
record_format Article
series Hong Kong Journal of Emergency Medicine
spelling doaj-art-3bc1cfecaa794514947a724b3951b0dd2025-08-20T01:47:57ZengWileyHong Kong Journal of Emergency Medicine1024-90792309-54072024-10-0131524225210.1002/hkj2.12041Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score levelWen‐Chen Lin0Chin‐Fu Chang1Yan‐Ren Lin2Chih‐Wen Twu3Mei‐Chu Chen4Yu‐Pin Ku5Kang‐Ping Lin6Ching‐Hsiung Lin7Department of Electrical Engineering Chung Yuan Christian University Taoyuan TaiwanQuality Management Department Changhua Christian Hospital Changhua TaiwanDepartment of Emergency and Critical Care Medicine Changhua Christian Hospital Changhua TaiwanQuality Management Department Changhua Christian Hospital Changhua TaiwanNursing Department Changhua Christian Hospital Changhua TaiwanDepartment of Industrial Engineering and Enterprise Information Tunghai University Taichung TaiwanDepartment of Electrical Engineering Chung Yuan Christian University Taoyuan TaiwanSuperintendent Room Changhua Christian Hospital Changhua TaiwanAbstract Background Improving the quality of medical care in hospitals is a major priority for all departments. The early warning score (EWS) trend is an effective early risk stratification tool that reflects the changes in patient condition and allows better assessment of deterioration risk. Objective The aim of this study was to investigate whether utilizing the trend of the modified early warning score (MEWS) level within 4 h of a patient's arrival in the emergency department (ED) could identify patients at risk of clinical deterioration at 8 h after arrival in the ED. Methods We conducted a retrospective observational study of non‐trauma patients who had at least two vital sign measurements (Glasgow Coma Scale score, heart rate, blood pressure, respiratory rate, and body temperature) within 8 h of arriving in the ED. The primary outcome was patients who had MEWS ≥ 4 at 8 h after arrival in the ED. We performed multivariate logistic regression analysis using age, sex, MEWS level at arrival in the ED, MEWS level within 4 h after arrival in the ED, and MEWS level trend over time. Results Among the 5825 patients, 680 (11.7%) were at risk of deterioration at 8 h after arrival in the ED. To predict the risk of deteriorating conditions (MEWS ≥ 4), utilizing the MEWS level trend within 4 h of arrival in the ED was more effective in identifying patients at risk of deterioration after 8 h of arrival in the ED compared to using a single MEWS value during the ED stay. The corresponding areas under the receiver operating characteristic curve were 0.756 (95% confidence interval (CI) 0.734–0.778) and 0.846 (95% CI 0.827–0.865), respectively (p < 0.01). Conclusions The proposed trend‐based predictive model for MEWS levels can alert healthcare personnel regarding patients at increased risk of deterioration (MEWS ≥ 4), potentially reducing mortality rates during ED stays.https://doi.org/10.1002/hkj2.12041early prediction of deterioration riskemergency departmentMEWS level trendmodified early warning score (MEWS)
spellingShingle Wen‐Chen Lin
Chin‐Fu Chang
Yan‐Ren Lin
Chih‐Wen Twu
Mei‐Chu Chen
Yu‐Pin Ku
Kang‐Ping Lin
Ching‐Hsiung Lin
Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score level
Hong Kong Journal of Emergency Medicine
early prediction of deterioration risk
emergency department
MEWS level trend
modified early warning score (MEWS)
title Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score level
title_full Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score level
title_fullStr Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score level
title_full_unstemmed Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score level
title_short Prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non‐traumatic patients using trends in modified early warning score level
title_sort prediction of clinical deterioration risk at 8 hours after arrival in emergency department in non traumatic patients using trends in modified early warning score level
topic early prediction of deterioration risk
emergency department
MEWS level trend
modified early warning score (MEWS)
url https://doi.org/10.1002/hkj2.12041
work_keys_str_mv AT wenchenlin predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel
AT chinfuchang predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel
AT yanrenlin predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel
AT chihwentwu predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel
AT meichuchen predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel
AT yupinku predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel
AT kangpinglin predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel
AT chinghsiunglin predictionofclinicaldeteriorationriskat8hoursafterarrivalinemergencydepartmentinnontraumaticpatientsusingtrendsinmodifiedearlywarningscorelevel