Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS)
Abstract Cognitive impairment and dementia have long been recognized as growing public health threats. Studies have found that air pollution is a potential risk factor for dementia, but the literature remains inconclusive. This study aimed to evaluate the association between three major air pollutan...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Geophysical Union (AGU)
2025-01-01
|
| Series: | GeoHealth |
| Subjects: | |
| Online Access: | https://doi.org/10.1029/2024GH001023 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832583585326956544 |
|---|---|
| author | Qingyang Zhu Yuebin Lyu Keyong Huang Jinhui Zhou Wenhao Wang Kyle Steenland Howard H. Chang Stefanie Ebelt Xiaoming Shi Yang Liu |
| author_facet | Qingyang Zhu Yuebin Lyu Keyong Huang Jinhui Zhou Wenhao Wang Kyle Steenland Howard H. Chang Stefanie Ebelt Xiaoming Shi Yang Liu |
| author_sort | Qingyang Zhu |
| collection | DOAJ |
| description | Abstract Cognitive impairment and dementia have long been recognized as growing public health threats. Studies have found that air pollution is a potential risk factor for dementia, but the literature remains inconclusive. This study aimed to evaluate the association between three major air pollutants (i.e., PM2.5, O3, and NO2) and cognitive impairment among the Chinese elderly population. Study participants were selected from the Chinese Longitudinal Health Longevity Survey (CLHLS) after 2005. We define cognitive impairment as a Chinese Mini‐Mental‐State Exam (CMMSE) score <24. The associations of air pollution with cognitive impairment and CMMSE score were evaluated with a logistic regression model and a linear mixed‐effect model with random intercepts, respectively. A total of 3,887 participants were enrolled in this study. Of the 2,882 participants who completed at least one follow‐up visit, 931 eventually developed cognitive impairment. In single‐pollutant models, we found that yearly average PM2.5 and NO2 as well as warm season O3, were positively associated with cognitive impairment. NO2 remained positively associated with cognitive impairment in the multi‐pollutant model. The linear mixed‐effect models revealed that warm season O3 and yearly average NO2 were significantly associated with decreased CMMSE scores. Our research has established a positive association between cognitive impairment and air pollution in China. These findings underscore the imperative for the next iteration of China's Air Pollution Prevention and Control Action Plan to broaden its focus to encompass gaseous air pollutants since mitigating single air pollutant is insufficient to protect the aging population. |
| format | Article |
| id | doaj-art-3bbf0764d6c54f3dba34542e1854a3b3 |
| institution | Kabale University |
| issn | 2471-1403 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | American Geophysical Union (AGU) |
| record_format | Article |
| series | GeoHealth |
| spelling | doaj-art-3bbf0764d6c54f3dba34542e1854a3b32025-01-28T10:40:37ZengAmerican Geophysical Union (AGU)GeoHealth2471-14032025-01-0191n/an/a10.1029/2024GH001023Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS)Qingyang Zhu0Yuebin Lyu1Keyong Huang2Jinhui Zhou3Wenhao Wang4Kyle Steenland5Howard H. Chang6Stefanie Ebelt7Xiaoming Shi8Yang Liu9Gangarosa Department of Environmental Health Rollins School of Public Health Emory University Atlanta GA USAChina CDC Key Laboratory of Environment and Population Health Chinese Center for Disease Control and Prevention National Institute of Environmental Health Beijing ChinaKey Laboratory of Cardiovascular Epidemiology & Department of Epidemiology Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing ChinaChina CDC Key Laboratory of Environment and Population Health Chinese Center for Disease Control and Prevention National Institute of Environmental Health Beijing ChinaGangarosa Department of Environmental Health Rollins School of Public Health Emory University Atlanta GA USAGangarosa Department of Environmental Health Rollins School of Public Health Emory University Atlanta GA USADepartment of Biostatistics and Bioinformatics Rollins School of Public Health Emory University Atlanta GA USAGangarosa Department of Environmental Health Rollins School of Public Health Emory University Atlanta GA USAChina CDC Key Laboratory of Environment and Population Health Chinese Center for Disease Control and Prevention National Institute of Environmental Health Beijing ChinaGangarosa Department of Environmental Health Rollins School of Public Health Emory University Atlanta GA USAAbstract Cognitive impairment and dementia have long been recognized as growing public health threats. Studies have found that air pollution is a potential risk factor for dementia, but the literature remains inconclusive. This study aimed to evaluate the association between three major air pollutants (i.e., PM2.5, O3, and NO2) and cognitive impairment among the Chinese elderly population. Study participants were selected from the Chinese Longitudinal Health Longevity Survey (CLHLS) after 2005. We define cognitive impairment as a Chinese Mini‐Mental‐State Exam (CMMSE) score <24. The associations of air pollution with cognitive impairment and CMMSE score were evaluated with a logistic regression model and a linear mixed‐effect model with random intercepts, respectively. A total of 3,887 participants were enrolled in this study. Of the 2,882 participants who completed at least one follow‐up visit, 931 eventually developed cognitive impairment. In single‐pollutant models, we found that yearly average PM2.5 and NO2 as well as warm season O3, were positively associated with cognitive impairment. NO2 remained positively associated with cognitive impairment in the multi‐pollutant model. The linear mixed‐effect models revealed that warm season O3 and yearly average NO2 were significantly associated with decreased CMMSE scores. Our research has established a positive association between cognitive impairment and air pollution in China. These findings underscore the imperative for the next iteration of China's Air Pollution Prevention and Control Action Plan to broaden its focus to encompass gaseous air pollutants since mitigating single air pollutant is insufficient to protect the aging population.https://doi.org/10.1029/2024GH001023air pollutioncognitive impairmentCLHLSconcentration‐response relationship |
| spellingShingle | Qingyang Zhu Yuebin Lyu Keyong Huang Jinhui Zhou Wenhao Wang Kyle Steenland Howard H. Chang Stefanie Ebelt Xiaoming Shi Yang Liu Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) GeoHealth air pollution cognitive impairment CLHLS concentration‐response relationship |
| title | Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) |
| title_full | Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) |
| title_fullStr | Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) |
| title_full_unstemmed | Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) |
| title_short | Air Pollution and Cognitive Impairment Among the Chinese Elderly Population: An Analysis of the Chinese Longitudinal Healthy Longevity Survey (CLHLS) |
| title_sort | air pollution and cognitive impairment among the chinese elderly population an analysis of the chinese longitudinal healthy longevity survey clhls |
| topic | air pollution cognitive impairment CLHLS concentration‐response relationship |
| url | https://doi.org/10.1029/2024GH001023 |
| work_keys_str_mv | AT qingyangzhu airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT yuebinlyu airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT keyonghuang airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT jinhuizhou airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT wenhaowang airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT kylesteenland airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT howardhchang airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT stefanieebelt airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT xiaomingshi airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls AT yangliu airpollutionandcognitiveimpairmentamongthechineseelderlypopulationananalysisofthechineselongitudinalhealthylongevitysurveyclhls |