The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying Hens

Trehalose, a disaccharide consisting of two D-glucose molecules, is present in a variety of organisms, including bacteria, yeast, fungi, insects, and plants. In plants, it functions as a source of energy and carbon, and in yeast and plants, it serves as a signaling molecule, influencing metabolic pa...

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Main Authors: Fernando Perazzo Costa, Isabelle Kaneko, Thamires Ferreira, Jorge Muniz, Eliane Silva, Adiel Lima, Raul Lima Neto, Matheus Ramalho Lima, Thiago Moreira
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Animals
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Online Access:https://www.mdpi.com/2076-2615/15/9/1318
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author Fernando Perazzo Costa
Isabelle Kaneko
Thamires Ferreira
Jorge Muniz
Eliane Silva
Adiel Lima
Raul Lima Neto
Matheus Ramalho Lima
Thiago Moreira
author_facet Fernando Perazzo Costa
Isabelle Kaneko
Thamires Ferreira
Jorge Muniz
Eliane Silva
Adiel Lima
Raul Lima Neto
Matheus Ramalho Lima
Thiago Moreira
author_sort Fernando Perazzo Costa
collection DOAJ
description Trehalose, a disaccharide consisting of two D-glucose molecules, is present in a variety of organisms, including bacteria, yeast, fungi, insects, and plants. In plants, it functions as a source of energy and carbon, and in yeast and plants, it serves as a signaling molecule, influencing metabolic pathways and growth regulation. Additionally, it plays a role in protecting proteins and cell membranes from stress-induced damage. This study aims to assess the optimal level of trehalose supplementation in the diets of layer hens aged 34 to 49 weeks, addressing the limited existing literature on its effects on productivity. Experimental diets, designed in accordance with nutritional recommendations, were formulated to contain six different levels of trehalose (0, 0.05, 0.10, 0.30, 0.60, and 1.00%). The study was conducted over five 21-day periods, during which various performance parameters were evaluated. The results indicated that trehalose supplementation at levels of 0.05%, 0.10%, and 0.30% led to increased feed intake (FI) compared to the 1.00% level (<i>p</i> < 0.05). Furthermore, the highest trehalose level (1.00%) significantly reduced the feed conversion ratio by egg mass (FCRem) compared to both the control group and the other supplementation levels; however, the feed conversion ratio by dry matter (FCRDz) remained consistent across all treatments. The levels of 0.05%, 0.10%, and 0.30% exhibited superior FCREm and FCRDz compared to the 1.00% level. Egg weight (EW) was higher in the trehalose-supplemented groups compared to the control group. Additionally, the 1.00% trehalose treatment was found to be the most effective in terms of relative weights of shells (RWS), and egg mass (EM) was higher at all trehalose levels compared to the control group. The antioxidant status, as measured by malondialdehyde (MDA) levels, indicated that supplementation with 0.30% and 0.60% trehalose had a protective effect against oxidative stress, although the 1.00% level resulted in increased MDA levels. Total weight (TW) was highest in the 0.30% treatment group, and bone strength (BS) improved in the groups supplemented with 0.10% and 1.00% trehalose. Other parameters, including lipid content (L), dry matter (DM), phosphorus (P), and calcium (Ca), did not show any significant differences among the treatment groups. In conclusion, supplementation with 1.00% trehalose enhances feed efficiency, egg weight, and quality, with minimal impact on lipid peroxidation, while potentially providing benefits for gut health and egg quality.
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spelling doaj-art-3bbc04540b2748fa98c2ed7015d76e122025-08-20T02:59:07ZengMDPI AGAnimals2076-26152025-05-01159131810.3390/ani15091318The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying HensFernando Perazzo Costa0Isabelle Kaneko1Thamires Ferreira2Jorge Muniz3Eliane Silva4Adiel Lima5Raul Lima Neto6Matheus Ramalho Lima7Thiago Moreira8Animal Science, Federal University of Paraiba, Campus Areia, Areia 59397-000, PB, BrazilAnimal Science, Federal University of Paraiba, Campus Areia, Areia 59397-000, PB, BrazilAnimal Science, Federal University of Paraiba, Campus Areia, Areia 59397-000, PB, BrazilAnimal Science, Federal University of Paraiba, Campus Areia, Areia 59397-000, PB, BrazilCJ do Brasil, Sao Paulo 01310-930, SP, BrazilAnimal Science, Federal University of Paraiba, Campus Areia, Areia 59397-000, PB, BrazilAnimal Science, Federal University of Paraiba, Campus Areia, Areia 59397-000, PB, BrazilAnimal Science, Federal Rural University of the Semi-Arid Region, Campus Mossoro, Mossoro 59625-900, RN, BrazilAnimal Science, Federal University of Paraiba, Campus Areia, Areia 59397-000, PB, BrazilTrehalose, a disaccharide consisting of two D-glucose molecules, is present in a variety of organisms, including bacteria, yeast, fungi, insects, and plants. In plants, it functions as a source of energy and carbon, and in yeast and plants, it serves as a signaling molecule, influencing metabolic pathways and growth regulation. Additionally, it plays a role in protecting proteins and cell membranes from stress-induced damage. This study aims to assess the optimal level of trehalose supplementation in the diets of layer hens aged 34 to 49 weeks, addressing the limited existing literature on its effects on productivity. Experimental diets, designed in accordance with nutritional recommendations, were formulated to contain six different levels of trehalose (0, 0.05, 0.10, 0.30, 0.60, and 1.00%). The study was conducted over five 21-day periods, during which various performance parameters were evaluated. The results indicated that trehalose supplementation at levels of 0.05%, 0.10%, and 0.30% led to increased feed intake (FI) compared to the 1.00% level (<i>p</i> < 0.05). Furthermore, the highest trehalose level (1.00%) significantly reduced the feed conversion ratio by egg mass (FCRem) compared to both the control group and the other supplementation levels; however, the feed conversion ratio by dry matter (FCRDz) remained consistent across all treatments. The levels of 0.05%, 0.10%, and 0.30% exhibited superior FCREm and FCRDz compared to the 1.00% level. Egg weight (EW) was higher in the trehalose-supplemented groups compared to the control group. Additionally, the 1.00% trehalose treatment was found to be the most effective in terms of relative weights of shells (RWS), and egg mass (EM) was higher at all trehalose levels compared to the control group. The antioxidant status, as measured by malondialdehyde (MDA) levels, indicated that supplementation with 0.30% and 0.60% trehalose had a protective effect against oxidative stress, although the 1.00% level resulted in increased MDA levels. Total weight (TW) was highest in the 0.30% treatment group, and bone strength (BS) improved in the groups supplemented with 0.10% and 1.00% trehalose. Other parameters, including lipid content (L), dry matter (DM), phosphorus (P), and calcium (Ca), did not show any significant differences among the treatment groups. In conclusion, supplementation with 1.00% trehalose enhances feed efficiency, egg weight, and quality, with minimal impact on lipid peroxidation, while potentially providing benefits for gut health and egg quality.https://www.mdpi.com/2076-2615/15/9/1318bone strengthdisaccharideegg productionlipid peroxidationperformance
spellingShingle Fernando Perazzo Costa
Isabelle Kaneko
Thamires Ferreira
Jorge Muniz
Eliane Silva
Adiel Lima
Raul Lima Neto
Matheus Ramalho Lima
Thiago Moreira
The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying Hens
Animals
bone strength
disaccharide
egg production
lipid peroxidation
performance
title The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying Hens
title_full The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying Hens
title_fullStr The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying Hens
title_full_unstemmed The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying Hens
title_short The Impact of Adding Trehalose to the Diet on Egg Quality and Tibia Strength in Light-Laying Hens
title_sort impact of adding trehalose to the diet on egg quality and tibia strength in light laying hens
topic bone strength
disaccharide
egg production
lipid peroxidation
performance
url https://www.mdpi.com/2076-2615/15/9/1318
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