Evaluation of the metabolic activity, angiogenic impacts, and GSK-3β signaling of the synthetic cannabinoid MMB-2201 on human cerebral microvascular endothelial cells

Evaluation of the metabolic activity, angiogenic impacts, and GSK-3β signaling of the synthetic cannabinoid MMB-2201 on human cerebral microvascular endothelial cells

Abstract Angiogenesis is an intrinsic physiological process involving the formation of new capillaries from existing ones. Synthetic cannabinoids refer to a class of human-made chemicals that are primarily designed to mimic the effects of delta-9-tetrahydrocannabinol, the primary psychoactive compou...

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Bibliographic Details
Main Authors: Laith Naser AL-Eitan, Saif Zuhair Alahmad, Sufyan Ali Ajeen, Ahmad Younis Altawil, Iliya Yacoub Khair, Hana Salah Abu Kharmah, Mansour Abdullah Alghamdi
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Cannabis Research
Subjects:
Angiogenesis
Cannabinoid receptors
GSK-3β
MMB-2201
VEGF
Synthetic cannabinoid
Online Access:https://doi.org/10.1186/s42238-024-00255-7
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