Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes Mellitus
Background: Obesity has been connected to a higher risk of acquiring a number of diseases, including cancer, type 2 diabetes mellitus (T2DM), hypertension, and cardiovascular disease. Periostin is a crucial regulator of the growth and maintenance of bones, teeth, and the heart. Objectives: The aim o...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-01-01
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| Series: | Medical Journal of Babylon |
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| Online Access: | https://doi.org/10.4103/MJBL.MJBL_794_23 |
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| author | Layla Othman Farhan Ahmed Abduljabar Al-Sabbagh Baydaa Ahmed Abed Ahlam M. Farhan Noor Ulhuda G. Mohammed |
| author_facet | Layla Othman Farhan Ahmed Abduljabar Al-Sabbagh Baydaa Ahmed Abed Ahlam M. Farhan Noor Ulhuda G. Mohammed |
| author_sort | Layla Othman Farhan |
| collection | DOAJ |
| description | Background: Obesity has been connected to a higher risk of acquiring a number of diseases, including cancer, type 2 diabetes mellitus (T2DM), hypertension, and cardiovascular disease. Periostin is a crucial regulator of the growth and maintenance of bones, teeth, and the heart. Objectives: The aim of the study was to estimate the level of (periostin, glycated hemoglobin [HbA1c], fasting serum [FBG], total cholesterol [TC], high-density lipoprotein [HDL], low-density lipoprotein [LDL], and triglycerides [TG]) in diabetic Iraqi women obese and nonobese. Materials and Methods: Ninety participants were chosen for this study: 30 nonobese female patients with T2DM (nonobese-T2DM), 30 obese female patients with T2DM (obese-T2DM), and 30 healthy participants. Age ranges between 35 and 65 years. Results: The result of the present study found a highly significant increase in the (body mass index [BMI], FBG, HbA1c, TC, TG, LDL, and periostin) in obese-T2DM and nonobese-T2DM when compared with the healthy control group, whereas HDL was lower in obese-T2DM and nonobese-T2DM when compared with the healthy control group. Conclusion: The current investigation discovered, in summary, that plasma periostin may function as a novel marker for insulin resistance, obesity, and inflammatory responses, which might be used to diagnose T2DM and obesity. |
| format | Article |
| id | doaj-art-3bb379041cf44addb34e4a65d6c09f7d |
| institution | DOAJ |
| issn | 1812-156X 2312-6760 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Medical Journal of Babylon |
| spelling | doaj-art-3bb379041cf44addb34e4a65d6c09f7d2025-08-20T03:09:42ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602025-01-0122115115510.4103/MJBL.MJBL_794_23Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes MellitusLayla Othman FarhanAhmed Abduljabar Al-SabbaghBaydaa Ahmed AbedAhlam M. FarhanNoor Ulhuda G. MohammedBackground: Obesity has been connected to a higher risk of acquiring a number of diseases, including cancer, type 2 diabetes mellitus (T2DM), hypertension, and cardiovascular disease. Periostin is a crucial regulator of the growth and maintenance of bones, teeth, and the heart. Objectives: The aim of the study was to estimate the level of (periostin, glycated hemoglobin [HbA1c], fasting serum [FBG], total cholesterol [TC], high-density lipoprotein [HDL], low-density lipoprotein [LDL], and triglycerides [TG]) in diabetic Iraqi women obese and nonobese. Materials and Methods: Ninety participants were chosen for this study: 30 nonobese female patients with T2DM (nonobese-T2DM), 30 obese female patients with T2DM (obese-T2DM), and 30 healthy participants. Age ranges between 35 and 65 years. Results: The result of the present study found a highly significant increase in the (body mass index [BMI], FBG, HbA1c, TC, TG, LDL, and periostin) in obese-T2DM and nonobese-T2DM when compared with the healthy control group, whereas HDL was lower in obese-T2DM and nonobese-T2DM when compared with the healthy control group. Conclusion: The current investigation discovered, in summary, that plasma periostin may function as a novel marker for insulin resistance, obesity, and inflammatory responses, which might be used to diagnose T2DM and obesity.https://doi.org/10.4103/MJBL.MJBL_794_23lipid profileobesityperiostintype 2 diabetes mellitus (t2dm) |
| spellingShingle | Layla Othman Farhan Ahmed Abduljabar Al-Sabbagh Baydaa Ahmed Abed Ahlam M. Farhan Noor Ulhuda G. Mohammed Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes Mellitus Medical Journal of Babylon lipid profile obesity periostin type 2 diabetes mellitus (t2dm) |
| title | Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes Mellitus |
| title_full | Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes Mellitus |
| title_fullStr | Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes Mellitus |
| title_full_unstemmed | Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes Mellitus |
| title_short | Study Effect of Periostin Level in Obese Iraqi Females Patients with Type 2 Diabetes Mellitus |
| title_sort | study effect of periostin level in obese iraqi females patients with type 2 diabetes mellitus |
| topic | lipid profile obesity periostin type 2 diabetes mellitus (t2dm) |
| url | https://doi.org/10.4103/MJBL.MJBL_794_23 |
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