Osteopetrosis-like disorders induced by osteoblast-specific retinoic acid signaling inhibition in mice

Osteopetrosis-like disorders induced by osteoblast-specific retinoic acid signaling inhibition in mice

Abstract Osteopetrosis is an inherited metabolic disease, characterized by increased bone density and narrow marrow cavity. Patients with severe osteopetrosis exhibit abnormal bone brittleness, anemia, and infection complications, which commonly cause death within the first decade of life. Pathologi...

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Main Authors: Siyuan Sun, Yuanqi Liu, Jiping Sun, Bingxin Zan, Yiwen Cui, Anting Jin, Hongyuan Xu, Xiangru Huang, Yanfei Zhu, Yiling Yang, Xin Gao, Tingwei Lu, Xinyu Wang, Jingyi Liu, Li Mei, Lei Shen, Qinggang Dai, Lingyong Jiang
Format: Article
Language:English
Published: Nature Publishing Group 2024-10-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-024-00353-5
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