Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers

Ivabradine, an If inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart f...

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Main Authors: Michael Liang, Aniket Puri, Gerard Devlin
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Cardiology Research and Practice
Online Access:http://dx.doi.org/10.4061/2009/179350
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author Michael Liang
Aniket Puri
Gerard Devlin
author_facet Michael Liang
Aniket Puri
Gerard Devlin
author_sort Michael Liang
collection DOAJ
description Ivabradine, an If inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart failure. Many patients with coronary artery disease have coexisting asthma or chronic obstructive airway disease, and most of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in therapeutic heart rate management especially in patients who are intolerant of beta-blockers.
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institution Kabale University
issn 2090-0597
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spelling doaj-art-3baffda66cb746c5b0376da8bfc9d7842025-08-20T03:55:41ZengWileyCardiology Research and Practice2090-05972009-01-01200910.4061/2009/179350179350Heart Rate and Cardiovascular Disease: An Alternative to Beta BlockersMichael Liang0Aniket Puri1Gerard Devlin2Department of Cardiology, Waikato Hospital, Pembroke & Selwyn Sts, Private Bag 3200, Hamilton 3240, New ZealandDepartment of Cardiology, Waikato Hospital, Pembroke & Selwyn Sts, Private Bag 3200, Hamilton 3240, New ZealandDepartment of Cardiology, Waikato Hospital, Pembroke & Selwyn Sts, Private Bag 3200, Hamilton 3240, New ZealandIvabradine, an If inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart failure. Many patients with coronary artery disease have coexisting asthma or chronic obstructive airway disease, and most of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in therapeutic heart rate management especially in patients who are intolerant of beta-blockers.http://dx.doi.org/10.4061/2009/179350
spellingShingle Michael Liang
Aniket Puri
Gerard Devlin
Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
Cardiology Research and Practice
title Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_full Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_fullStr Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_full_unstemmed Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_short Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_sort heart rate and cardiovascular disease an alternative to beta blockers
url http://dx.doi.org/10.4061/2009/179350
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AT aniketpuri heartrateandcardiovasculardiseaseanalternativetobetablockers
AT gerarddevlin heartrateandcardiovasculardiseaseanalternativetobetablockers