Gut microbiota drives structural variation of exogenous probiotics to enhance colonization

Gut microbiota drives structural variation of exogenous probiotics to enhance colonization

Probiotics encounter colonization resistance from native gut microbiomes, affecting their effectiveness. Genetic engineering of probiotics lacks universal applicability, as gut microbiotas are highly individualized. Here, we employed probiotic Lactiplantibacillus plantarum HNU082 (Lp082) to test whe...

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Bibliographic Details
Main Authors: Shuaiming Jiang, Shi Huang, Zeng Zhang, Wenyao Ma, Zhe Han, Yuan Song, Dongxue Huo, Weipeng Cui, Jiachao Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Gut-adapted strains
probiotic bacteria
Lactiplantibacillus plantarum HNU082
divergent evolution
structural variations
colonization
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2503371
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