Silencing of RpATG8 impairs the biogenesis of maternal autophagosomes in vitellogenic oocytes, but does not interrupt follicular atresia in the insect vector Rhodnius prolixus.

Silencing of RpATG8 impairs the biogenesis of maternal autophagosomes in vitellogenic oocytes, but does not interrupt follicular atresia in the insect vector Rhodnius prolixus.

Follicular atresia is the mechanism by which the oocyte contents are degraded during oogenesis in response to stress conditions, allowing the energetic resources stored in the developing oocytes to be reallocated to optimize female fitness. Autophagy is a conserved intracellular degradation pathway...

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Main Authors: Jéssica Pereira, Calebe Diogo, Ariene Fonseca, Larissa Bomfim, Pedro Cardoso, Anna Santos, Uilla Dittz, Kildare Miranda, Wanderley de Souza, Adriana Gioda, Enrique R D Calderon, Luciana Araripe, Rafaela Bruno, Isabela Ramos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://storage.googleapis.com/plos-corpus-prod/10.1371/journal.pntd.0008012/2/pntd.0008012.pdf?X-Goog-Algorithm=GOOG4-RSA-SHA256&X-Goog-Credential=wombat-sa%40plos-prod.iam.gserviceaccount.com%2F20210221%2Fauto%2Fstorage%2Fgoog4_request&X-Goog-Date=20210221T071503Z&X-Goog-Expires=3600&X-Goog-SignedHeaders=host&X-Goog-Signature=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