RNA-seq analysis identifies key genes and signaling pathways involved in androgen promotion of sebaceous gland proliferation in Hetian sheep

RNA-seq analysis identifies key genes and signaling pathways involved in androgen promotion of sebaceous gland proliferation in Hetian sheep

Abstract Sebaceous glands (SGs), essential elements of the skin barrier in sheep, are tightly regulated by the androgen signaling pathway. This study investigated how androgens influence SGs hyperplasia in sheep by combining morphological assessments with transcriptomic analysis. Histological examin...

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Bibliographic Details
Main Authors: Zhiya Feng, Zhigang Li, Wanwan Peng, Jianping Zhang, Chunyang Li, Ruijun Shi, Shuwei Li
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Hetian sheep
Skin
RNA-seq
Masson staining
GSEA
Online Access:https://doi.org/10.1038/s41598-025-08837-y
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