Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumption

Introduction: Leptospirosis is a zoonotic disease caused by pathogenic Leptospira spp.  Leptospirosis is maintained in an environment due to chronic kidney infection of a wide variety of domestic, peridomestic and wild reservoir mammals. In this study the role of pigs in maintenance of leptospires o...

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Main Authors: Ashutosh Verma, Esteban Soto, Oscar Illanes, Souvik Ghosh, Carmen Fuentealba
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2015-05-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/5727
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author Ashutosh Verma
Esteban Soto
Oscar Illanes
Souvik Ghosh
Carmen Fuentealba
author_facet Ashutosh Verma
Esteban Soto
Oscar Illanes
Souvik Ghosh
Carmen Fuentealba
author_sort Ashutosh Verma
collection DOAJ
description Introduction: Leptospirosis is a zoonotic disease caused by pathogenic Leptospira spp.  Leptospirosis is maintained in an environment due to chronic kidney infection of a wide variety of domestic, peridomestic and wild reservoir mammals. In this study the role of pigs in maintenance of leptospires on the Caribbean island of St. Kitts was investigated. Methodology: The condemned kidneys of 60 pigs slaughtered at a St. Kitts abattoir were screened by a quantitative-PCR for the presence of Leptospira spp. Positive samples were genotyped using a six-gene based multilocus sequence typing scheme. Results: Leptospiral DNA was detected in the kidneys of one of the 60 pigs. Multilocus sequence typing identified the infecting species to be L. interrogans. Conclusions: Detection of this zoonotic pathogen in the kidneys of a seemingly healthy pig raises concerns regarding the subclinical carriers of the disease among the island’s swine population.
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publisher The Journal of Infection in Developing Countries
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series Journal of Infection in Developing Countries
spelling doaj-art-3bab1e685ec2402bbafec0e37f83865d2025-08-20T02:57:12ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802015-05-0190510.3855/jidc.5727Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumptionAshutosh Verma0Esteban Soto1Oscar Illanes2Souvik Ghosh3Carmen Fuentealba4Ross University School of Veterinary Medicine, Basseterre, St. KittsRoss University School of Veterinary Medicine, Basseterre, St. KittsRoss University School of Veterinary Medicine, Basseterre, St. KittsRoss University School of Veterinary Medicine, Basseterre, St. KittsRoss University School of Veterinary Medicine, Basseterre, St. KittsIntroduction: Leptospirosis is a zoonotic disease caused by pathogenic Leptospira spp.  Leptospirosis is maintained in an environment due to chronic kidney infection of a wide variety of domestic, peridomestic and wild reservoir mammals. In this study the role of pigs in maintenance of leptospires on the Caribbean island of St. Kitts was investigated. Methodology: The condemned kidneys of 60 pigs slaughtered at a St. Kitts abattoir were screened by a quantitative-PCR for the presence of Leptospira spp. Positive samples were genotyped using a six-gene based multilocus sequence typing scheme. Results: Leptospiral DNA was detected in the kidneys of one of the 60 pigs. Multilocus sequence typing identified the infecting species to be L. interrogans. Conclusions: Detection of this zoonotic pathogen in the kidneys of a seemingly healthy pig raises concerns regarding the subclinical carriers of the disease among the island’s swine population. https://jidc.org/index.php/journal/article/view/5727LeptospirosisLeptospiraswinegenotypingMulti-locus sequence typing (MLST)
spellingShingle Ashutosh Verma
Esteban Soto
Oscar Illanes
Souvik Ghosh
Carmen Fuentealba
Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumption
Journal of Infection in Developing Countries
Leptospirosis
Leptospira
swine
genotyping
Multi-locus sequence typing (MLST)
title Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumption
title_full Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumption
title_fullStr Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumption
title_full_unstemmed Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumption
title_short Detection and genotyping of Leptospira spp. from the kidneys of a seemingly healthy pig slaughtered for human consumption
title_sort detection and genotyping of leptospira spp from the kidneys of a seemingly healthy pig slaughtered for human consumption
topic Leptospirosis
Leptospira
swine
genotyping
Multi-locus sequence typing (MLST)
url https://jidc.org/index.php/journal/article/view/5727
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