The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease
Aim of the Study This review investigates the relationship between physical activity and inflammatory bowel disease (IBD), focusing on inflammatory markers, gut microbiota composition, and disease activity. The objective is to examine how exercise intensities influence inflammation, microbial diver...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-01-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/57083 |
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| author | Paulina Jakubczyk Piotr Widera Justyna Helis Maciej Michalik Aleksandra Buczek Hubert Bigajski Aleksandra Banaś Olga Bilczewska Wiktoria Janik Marta Handschuh |
| author_facet | Paulina Jakubczyk Piotr Widera Justyna Helis Maciej Michalik Aleksandra Buczek Hubert Bigajski Aleksandra Banaś Olga Bilczewska Wiktoria Janik Marta Handschuh |
| author_sort | Paulina Jakubczyk |
| collection | DOAJ |
| description |
Aim of the Study
This review investigates the relationship between physical activity and inflammatory bowel disease (IBD), focusing on inflammatory markers, gut microbiota composition, and disease activity. The objective is to examine how exercise intensities influence inflammation, microbial diversity, and patient outcomes for IBD management.
Materials and Methods
A literature review synthesized peer-reviewed studies from 2010-2024 using PubMed, Scopus, and Embase databases, examining physical activity effects on inflammatory markers, gut microbiota, and clinical outcomes in IBD patients. Inclusion criteria emphasized human studies, excluding research unrelated to IBD or focused on animal models.
State of Knowledge
Moderate-intensity aerobic and resistance exercises reduce systemic inflammatory markers, (CRP and cytokines) and enhance gut microbiota diversity, increasing anti-inflammatory species. Low-to-moderate intensity activities improve quality of life in IBD patients. Exercise supports intestinal barrier integrity through mucin production and fatty acid synthesis. High-intensity exercise can worsen inflammation, necessitating tailored protocols.
Conclusions
Physical activity is a promising adjunctive therapy in IBD management. Moderate-intensity programs effectively maintain remission and enhance outcomes. Future research should focus on longitudinal studies, advanced omics technologies, and combined approaches with dietary and pharmacological therapies.
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| format | Article |
| id | doaj-art-3ba8d25f377540cf8f3b6eaa0d39b8cc |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-3ba8d25f377540cf8f3b6eaa0d39b8cc2025-01-21T08:23:00ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2025.37.57083The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel DiseasePaulina Jakubczyk0https://orcid.org/0000-0001-9821-7678Piotr Widera1https://orcid.org/0009-0008-7518-2482Justyna Helis2https://orcid.org/0009-0003-5657-2569Maciej Michalik3https://orcid.org/0009-0007-9778-8736Aleksandra Buczek4https://orcid.org/0009-0008-7534-7830Hubert Bigajski5https://orcid.org/0009-0007-0570-5367Aleksandra Banaś6https://orcid.org/0009-0009-5584-5944Olga Bilczewska7https://orcid.org/0009-0006-7097-1226Wiktoria Janik8https://orcid.org/0009-0006-8406-3309Marta Handschuh9https://orcid.org/0009-0005-1539-8589University Hospital of Karol Marcinkowski in Zielona GóraFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of SilesiaFaculty of Medical Sciences in Katowice, Medical University of Silesia Aim of the Study This review investigates the relationship between physical activity and inflammatory bowel disease (IBD), focusing on inflammatory markers, gut microbiota composition, and disease activity. The objective is to examine how exercise intensities influence inflammation, microbial diversity, and patient outcomes for IBD management. Materials and Methods A literature review synthesized peer-reviewed studies from 2010-2024 using PubMed, Scopus, and Embase databases, examining physical activity effects on inflammatory markers, gut microbiota, and clinical outcomes in IBD patients. Inclusion criteria emphasized human studies, excluding research unrelated to IBD or focused on animal models. State of Knowledge Moderate-intensity aerobic and resistance exercises reduce systemic inflammatory markers, (CRP and cytokines) and enhance gut microbiota diversity, increasing anti-inflammatory species. Low-to-moderate intensity activities improve quality of life in IBD patients. Exercise supports intestinal barrier integrity through mucin production and fatty acid synthesis. High-intensity exercise can worsen inflammation, necessitating tailored protocols. Conclusions Physical activity is a promising adjunctive therapy in IBD management. Moderate-intensity programs effectively maintain remission and enhance outcomes. Future research should focus on longitudinal studies, advanced omics technologies, and combined approaches with dietary and pharmacological therapies. https://apcz.umk.pl/QS/article/view/57083inflammatory bowel diseaseCrohn's diseaseulcerative colitisphysical activity |
| spellingShingle | Paulina Jakubczyk Piotr Widera Justyna Helis Maciej Michalik Aleksandra Buczek Hubert Bigajski Aleksandra Banaś Olga Bilczewska Wiktoria Janik Marta Handschuh The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease Quality in Sport inflammatory bowel disease Crohn's disease ulcerative colitis physical activity |
| title | The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease |
| title_full | The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease |
| title_fullStr | The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease |
| title_full_unstemmed | The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease |
| title_short | The Influence of Physical Activity on Inflammatory Markers, Intestinal Microbiota Composition and Disease Activity in Inflammatory Bowel Disease |
| title_sort | influence of physical activity on inflammatory markers intestinal microbiota composition and disease activity in inflammatory bowel disease |
| topic | inflammatory bowel disease Crohn's disease ulcerative colitis physical activity |
| url | https://apcz.umk.pl/QS/article/view/57083 |
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