Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern Nigeria
Study’s Novelty/Excerpt • This study investigates the occurrence and antibiotic resistance profiles of Vibrio species isolated from landfill soils in Zaria Metropolis, with a focus on environmental reservoirs of antibiotic resistance. • The research uniquely identifies a high prevalence of Vib...
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Umaru Musa Yar'adua University, Katsina, Nigeria
2024-06-01
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| Series: | UMYU Journal of Microbiology Research |
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| Online Access: | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/597 |
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| author | Yomi Marie Carole Nyandjou Abubakar Umar |
| author_facet | Yomi Marie Carole Nyandjou Abubakar Umar |
| author_sort | Yomi Marie Carole Nyandjou |
| collection | DOAJ |
| description | Study’s Novelty/Excerpt
• This study investigates the occurrence and antibiotic resistance profiles of Vibrio species isolated from landfill soils in Zaria Metropolis, with a focus on environmental reservoirs of antibiotic resistance.
• The research uniquely identifies a high prevalence of Vibrio cholerae non-O1 among the isolates and reveals significant multidrug resistance (MDR), particularly against Ampicillin, while also showing complete susceptibility to Gentamicin and Chloramphenicol.
• These findings highlight the potential for landfills to serve as environmental reservoirs of antibiotic resistance, underscoring the need for further research to understand the implications for public health and environmental management.
Full Abstract
Antibiotic resistance in bacteria presents a major risk to public health and the environment. Infections caused by Vibrio species continue to be a serious public health concern. This study investigated the occurrence and antibiotic resistance profiles of Vibrio species isolates from landfill soils in Zaria Metropolis. A total of one hundred and twenty (120) soil samples were collected from designated landfills in four locations in Sabon-Gari, Samaru, Tudun-Wada, and Zaria City. Vibrio species were isolated using Thiosulphate citrate bile salt sucrose (TCBS) agar. Bacteriological analysis of the soil samples revealed 9(7.50%) Vibrio species isolates with Vibrio cholerae non-O1 exhibiting the highest prevalence of 4 (3.33%) among all isolates. Using the Kirby-Bauer method, the isolates were tested for susceptibility against ten commonly used antibiotics belonging to three different classes. The highest resistance was to Ampicillin (88. 89%), while all the isolates (100%) showed susceptibility to Gentamicin and Chloramphenicol. Five isolates (55.56%) were Multidrug Resistance (MDR). The highest Multidrug Resistance (MDR, 60%) was observed in Vibrio cholerae non-O1. The isolate resistant to the highest number of antibiotics was obtained from the Tudun-Wada sample location. Three isolates (33.33%) showed resistance to 4 antibiotics, while 2 isolates, 1(11.11%) each were resistant to 5 and 6 antibiotics. The isolates were Multiple Antibiotic Resistance (MAR) to 4-6 antibiotics, and four different phenotypic resistance profiles were observed among them. The origin and varying levels of resistance to multiple antibiotics indicated could be traced to the faecal constituent of the waste in landfills produced by people or animals that have been treated indiscriminately with various antibiotics or items containing residual antimicrobial agents disposed of in dump soils, highlighting the potential environmental reservoirs of antibiotic resistance and call for further research to understand the implications for public health and environmental management. |
| format | Article |
| id | doaj-art-3ba0fcd37b314ba78493e45378dc40c9 |
| institution | OA Journals |
| issn | 2616-0668 2814-1822 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | Umaru Musa Yar'adua University, Katsina, Nigeria |
| record_format | Article |
| series | UMYU Journal of Microbiology Research |
| spelling | doaj-art-3ba0fcd37b314ba78493e45378dc40c92025-08-20T01:52:38ZengUmaru Musa Yar'adua University, Katsina, NigeriaUMYU Journal of Microbiology Research2616-06682814-18222024-06-0125225810.47430/ujmr.2493.031597Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern NigeriaYomi Marie Carole Nyandjou0https://orcid.org/0009-0004-3948-1144Abubakar Umar1https://orcid.org/0009-0007-6008-5391Department of Microbiology, Federal University Gusau, Zamfara State, NigeriaDepartment of Microbiology, Federal University Gusau, Zamfara State, NigeriaStudy’s Novelty/Excerpt • This study investigates the occurrence and antibiotic resistance profiles of Vibrio species isolated from landfill soils in Zaria Metropolis, with a focus on environmental reservoirs of antibiotic resistance. • The research uniquely identifies a high prevalence of Vibrio cholerae non-O1 among the isolates and reveals significant multidrug resistance (MDR), particularly against Ampicillin, while also showing complete susceptibility to Gentamicin and Chloramphenicol. • These findings highlight the potential for landfills to serve as environmental reservoirs of antibiotic resistance, underscoring the need for further research to understand the implications for public health and environmental management. Full Abstract Antibiotic resistance in bacteria presents a major risk to public health and the environment. Infections caused by Vibrio species continue to be a serious public health concern. This study investigated the occurrence and antibiotic resistance profiles of Vibrio species isolates from landfill soils in Zaria Metropolis. A total of one hundred and twenty (120) soil samples were collected from designated landfills in four locations in Sabon-Gari, Samaru, Tudun-Wada, and Zaria City. Vibrio species were isolated using Thiosulphate citrate bile salt sucrose (TCBS) agar. Bacteriological analysis of the soil samples revealed 9(7.50%) Vibrio species isolates with Vibrio cholerae non-O1 exhibiting the highest prevalence of 4 (3.33%) among all isolates. Using the Kirby-Bauer method, the isolates were tested for susceptibility against ten commonly used antibiotics belonging to three different classes. The highest resistance was to Ampicillin (88. 89%), while all the isolates (100%) showed susceptibility to Gentamicin and Chloramphenicol. Five isolates (55.56%) were Multidrug Resistance (MDR). The highest Multidrug Resistance (MDR, 60%) was observed in Vibrio cholerae non-O1. The isolate resistant to the highest number of antibiotics was obtained from the Tudun-Wada sample location. Three isolates (33.33%) showed resistance to 4 antibiotics, while 2 isolates, 1(11.11%) each were resistant to 5 and 6 antibiotics. The isolates were Multiple Antibiotic Resistance (MAR) to 4-6 antibiotics, and four different phenotypic resistance profiles were observed among them. The origin and varying levels of resistance to multiple antibiotics indicated could be traced to the faecal constituent of the waste in landfills produced by people or animals that have been treated indiscriminately with various antibiotics or items containing residual antimicrobial agents disposed of in dump soils, highlighting the potential environmental reservoirs of antibiotic resistance and call for further research to understand the implications for public health and environmental management.https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/597vibrio speciesantimicrobial resistancemultidrug resistancepublic health and environmental managementzaria metropolis |
| spellingShingle | Yomi Marie Carole Nyandjou Abubakar Umar Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern Nigeria UMYU Journal of Microbiology Research vibrio species antimicrobial resistance multidrug resistance public health and environmental management zaria metropolis |
| title | Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern Nigeria |
| title_full | Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern Nigeria |
| title_fullStr | Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern Nigeria |
| title_full_unstemmed | Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern Nigeria |
| title_short | Study on Antibiotic Resistance Profiles Exhibited by Vibrio Species Isolated from Landfill Soils in Zaria Metropolis, Northern Nigeria |
| title_sort | study on antibiotic resistance profiles exhibited by vibrio species isolated from landfill soils in zaria metropolis northern nigeria |
| topic | vibrio species antimicrobial resistance multidrug resistance public health and environmental management zaria metropolis |
| url | https://ujmr.umyu.edu.ng/index.php/ujmr/article/view/597 |
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