Aging and head and neck cancer insights from single cell and spatial transcriptomic analyses

Aging and head and neck cancer insights from single cell and spatial transcriptomic analyses

Abstract Background Head and neck squamous cell carcinoma(HNSCC) is the sixth most common malignancy worldwide, with more than 890,000 new cases and 450,000 deaths annually. Its major risk factors include smoking, alcohol abuse, aging, and poor oral hygiene. Due to the lack of early and effective de...

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Main Authors: Yi Pei, Zhuying Mou, Lai Jiang, Jinyan Yang, Yuheng Gu, Jie Min, Lingyi Sunzhang, Nan Xiong, Xiang Xu, Hao Chi, Ke Xu, Sinian Liu, Huiyan Luo
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
Subjects:
Spatial transcriptomics
Single-cell RNA sequening
Head and neck cancer
Pathogenesis
Aging-related genes
Integrative analysis
Online Access:https://doi.org/10.1007/s12672-024-01672-z
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