Enhanced bioactivity and degradation behavior of zinc via micro-arc anodization for biomedical applications

Zinc-based alloys have attracted increasing interest as absorbable implant metals due to their suitable degradation rate and biocompatibility. However, a high concentration of Zn2+ due to the degradation process results in high cytotoxicity, and low osteogenesis remains a problem. In this work, a co...

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Bibliographic Details
Main Authors: Dong Hongzhou, Xu Weize, Virtanen Sannakaisa, Wang Yuxin
Format: Article
Language:English
Published: De Gruyter 2025-02-01
Series:High Temperature Materials and Processes
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Online Access:https://doi.org/10.1515/htmp-2024-0065
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Summary:Zinc-based alloys have attracted increasing interest as absorbable implant metals due to their suitable degradation rate and biocompatibility. However, a high concentration of Zn2+ due to the degradation process results in high cytotoxicity, and low osteogenesis remains a problem. In this work, a compact coating well integrated into the substrate was fabricated on the surface of zinc via micro-arc oxidation (MAO). The coating is mainly composed of ZnO. The addition of phosphate in the coating reinforced the adhesive strength between Zn and the coating. Electrochemical measurements demonstrate a superior corrosion resistance of MAO-P samples as compared to the substrate. Long-term immersion measurements in simulated body fluid indicate that the coating improved the bioactivity of the substrate, which is promising in view of orthopedic applications.
ISSN:2191-0324