Immunogenic cell death biomarkers for sepsis diagnosis and mechanism via integrated bioinformatics

Immunogenic cell death biomarkers for sepsis diagnosis and mechanism via integrated bioinformatics

Abstract Immunogenic cell death (ICD) has been implicated in sepsis, a condition with high mortality, through mechanisms involving endoplasmic reticulum stress and other pathophysiological pathways. This study aimed to identify and validate ICD-related biomarkers for sepsis diagnosis and to elucidat...

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Bibliographic Details
Main Authors: Guansheng Li, Xiaoxing Tian, Enyao Wei, Feng Zhang, Huang Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Sepsis
Immunogenic cell death
Biomarkers
Machine learning
Immune infiltration analysis
Online Access:https://doi.org/10.1038/s41598-025-03282-3
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