COVID-19 Ricochets on Kidney Transplant and Hemodialysis Patients
Background/Aims: An impaired immune response affects Coronavirus 2019 (COVID-19) disease progression. Immunities of both hemodialysis (HD) and Kidney Transplant (KTx) patients have already been suppressed. This study evaluated the prognostic laboratory results in HD and KTx patients with COVID-19. M...
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| Format: | Article |
| Language: | English |
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Selcuk University Press
2023-06-01
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| Series: | Genel Tıp Dergisi |
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| Online Access: | https://dergipark.org.tr/tr/download/article-file/2954217 |
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| author | Ali Kürşat Tuna Hilal Akay Çizmecioglu Mevlüt Hakan Göktepe Ahmet Cizmecioglu |
| author_facet | Ali Kürşat Tuna Hilal Akay Çizmecioglu Mevlüt Hakan Göktepe Ahmet Cizmecioglu |
| author_sort | Ali Kürşat Tuna |
| collection | DOAJ |
| description | Background/Aims: An impaired immune response affects Coronavirus 2019 (COVID-19) disease progression. Immunities of both hemodialysis (HD) and Kidney Transplant (KTx) patients have already been suppressed. This study evaluated the prognostic laboratory results in HD and KTx patients with COVID-19.
Methods: This retrospective, case-control study was conducted with PCR (+) COVID-19 HD and KTx patients and a control group. All patients were divided into two subgroups according to disease severity. Patients' demographic records and laboratory results were obtained from the follow-up files.
Results: A total of 30 HD, 20 KTx patients, and 40 control groups were involved in the study. Gender and hospitalization duration did not differ between the groups. There was a 10% mortality rate in the KTx group and 27% in the HD group. Lung involvement in Computed Tomography (CT) was higher in HD patients (47%) than in KTx (25%). In subgroup evaluations, the most prominent laboratory values were fibrinogen in HD patients and LDH and Ferritin in KTx patients in determining disease severity.
Conclusions: Early hospitalization and treatment implementations will be associated with a good prognosis in HD and KTx patients since CT and laboratory results are not predictive in these groups of patients during the COVID-19 pandemic. |
| format | Article |
| id | doaj-art-3b8c72c5f64c4a65b27e1d2dfe97166c |
| institution | Kabale University |
| issn | 2602-3741 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Genel Tıp Dergisi |
| spelling | doaj-art-3b8c72c5f64c4a65b27e1d2dfe97166c2025-01-02T20:59:24ZengSelcuk University PressGenel Tıp Dergisi2602-37412023-06-0133330931510.54005/geneltip.1251579154COVID-19 Ricochets on Kidney Transplant and Hemodialysis PatientsAli Kürşat Tuna0Hilal Akay Çizmecioglu1Mevlüt Hakan Göktepe2Ahmet Cizmecioglu3NECMETTIN ERBAKAN UNIVERSITY, MERAM SCHOOL OF MEDICINE, MERAM MEDICINE PR.NECMETTIN ERBAKAN UNIVERSITY, MERAM SCHOOL OF MEDICINE, MERAM MEDICINE PR.NECMETTIN ERBAKAN UNIVERSITY, MERAM SCHOOL OF MEDICINESELCUK UNIVERSITY, SCHOOL OF MEDICINEBackground/Aims: An impaired immune response affects Coronavirus 2019 (COVID-19) disease progression. Immunities of both hemodialysis (HD) and Kidney Transplant (KTx) patients have already been suppressed. This study evaluated the prognostic laboratory results in HD and KTx patients with COVID-19. Methods: This retrospective, case-control study was conducted with PCR (+) COVID-19 HD and KTx patients and a control group. All patients were divided into two subgroups according to disease severity. Patients' demographic records and laboratory results were obtained from the follow-up files. Results: A total of 30 HD, 20 KTx patients, and 40 control groups were involved in the study. Gender and hospitalization duration did not differ between the groups. There was a 10% mortality rate in the KTx group and 27% in the HD group. Lung involvement in Computed Tomography (CT) was higher in HD patients (47%) than in KTx (25%). In subgroup evaluations, the most prominent laboratory values were fibrinogen in HD patients and LDH and Ferritin in KTx patients in determining disease severity. Conclusions: Early hospitalization and treatment implementations will be associated with a good prognosis in HD and KTx patients since CT and laboratory results are not predictive in these groups of patients during the COVID-19 pandemic.https://dergipark.org.tr/tr/download/article-file/2954217covid-19disease severityhemodialysiskidney transplantationcovid-19böbrek naklihemodiyalizhastalık şiddeti |
| spellingShingle | Ali Kürşat Tuna Hilal Akay Çizmecioglu Mevlüt Hakan Göktepe Ahmet Cizmecioglu COVID-19 Ricochets on Kidney Transplant and Hemodialysis Patients Genel Tıp Dergisi covid-19 disease severity hemodialysis kidney transplantation covid-19 böbrek nakli hemodiyaliz hastalık şiddeti |
| title | COVID-19 Ricochets on Kidney Transplant and Hemodialysis Patients |
| title_full | COVID-19 Ricochets on Kidney Transplant and Hemodialysis Patients |
| title_fullStr | COVID-19 Ricochets on Kidney Transplant and Hemodialysis Patients |
| title_full_unstemmed | COVID-19 Ricochets on Kidney Transplant and Hemodialysis Patients |
| title_short | COVID-19 Ricochets on Kidney Transplant and Hemodialysis Patients |
| title_sort | covid 19 ricochets on kidney transplant and hemodialysis patients |
| topic | covid-19 disease severity hemodialysis kidney transplantation covid-19 böbrek nakli hemodiyaliz hastalık şiddeti |
| url | https://dergipark.org.tr/tr/download/article-file/2954217 |
| work_keys_str_mv | AT alikursattuna covid19ricochetsonkidneytransplantandhemodialysispatients AT hilalakaycizmecioglu covid19ricochetsonkidneytransplantandhemodialysispatients AT mevluthakangoktepe covid19ricochetsonkidneytransplantandhemodialysispatients AT ahmetcizmecioglu covid19ricochetsonkidneytransplantandhemodialysispatients |