Nanosystems for modulation of immune responses in periodontal therapy: a mini-review
Periodontitis is one of the most common oral diseases. It is generally treated by non-surgical and/or surgical therapy with adjunctive approaches for prevention and control. The current understanding of the pathogenesis of periodontitis has unraveled the importance of the inflammatory and immune rea...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Dental Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fdmed.2024.1509775/full |
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| author | Anirudh B. Acharya Usha Hegde Swetha Acharya |
| author_facet | Anirudh B. Acharya Usha Hegde Swetha Acharya |
| author_sort | Anirudh B. Acharya |
| collection | DOAJ |
| description | Periodontitis is one of the most common oral diseases. It is generally treated by non-surgical and/or surgical therapy with adjunctive approaches for prevention and control. The current understanding of the pathogenesis of periodontitis has unraveled the importance of the inflammatory and immune reactions to combat periodontitis whose etiology is an overlap of microbial, genetic, and environmental factors in a susceptible host. Based on this premise, many therapeutic modalities have been investigated or attempted to resolve this inflammatory disease. Amongst these, nanomedicine has been shown to have therapeutic applications in periodontitis, especially focused on immunomodulation because periodontitis is characterized by over-reactive immune response. This mini-review explores the potential of nanosystems in treating periodontitis by providing an overview of the research efforts in this field of therapeutics. The unique physicochemical and targeting properties of nanosystems seem to be potentially effective platforms for treating periodontitis. |
| format | Article |
| id | doaj-art-3b86ab2c3c0144ad9b2edc5aa203dfa5 |
| institution | Kabale University |
| issn | 2673-4915 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Dental Medicine |
| spelling | doaj-art-3b86ab2c3c0144ad9b2edc5aa203dfa52025-01-06T06:59:22ZengFrontiers Media S.A.Frontiers in Dental Medicine2673-49152025-01-01510.3389/fdmed.2024.15097751509775Nanosystems for modulation of immune responses in periodontal therapy: a mini-reviewAnirudh B. Acharya0Usha Hegde1Swetha Acharya2Department of Restorative Dentistry, College of Dental Medicine, University of Sharjah, Sharjah, United Arab EmiratesDepartment of Oral Pathology, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysore, Karnataka, IndiaDepartment of Oral Pathology, JSS Dental College and Hospital, JSS Academy of Higher Education and Research (JSSAHER), Mysore, Karnataka, IndiaPeriodontitis is one of the most common oral diseases. It is generally treated by non-surgical and/or surgical therapy with adjunctive approaches for prevention and control. The current understanding of the pathogenesis of periodontitis has unraveled the importance of the inflammatory and immune reactions to combat periodontitis whose etiology is an overlap of microbial, genetic, and environmental factors in a susceptible host. Based on this premise, many therapeutic modalities have been investigated or attempted to resolve this inflammatory disease. Amongst these, nanomedicine has been shown to have therapeutic applications in periodontitis, especially focused on immunomodulation because periodontitis is characterized by over-reactive immune response. This mini-review explores the potential of nanosystems in treating periodontitis by providing an overview of the research efforts in this field of therapeutics. The unique physicochemical and targeting properties of nanosystems seem to be potentially effective platforms for treating periodontitis.https://www.frontiersin.org/articles/10.3389/fdmed.2024.1509775/fullnanotechnologyimmunomodulationnanosystemsnanomedicineperiodontitistherapy |
| spellingShingle | Anirudh B. Acharya Usha Hegde Swetha Acharya Nanosystems for modulation of immune responses in periodontal therapy: a mini-review Frontiers in Dental Medicine nanotechnology immunomodulation nanosystems nanomedicine periodontitis therapy |
| title | Nanosystems for modulation of immune responses in periodontal therapy: a mini-review |
| title_full | Nanosystems for modulation of immune responses in periodontal therapy: a mini-review |
| title_fullStr | Nanosystems for modulation of immune responses in periodontal therapy: a mini-review |
| title_full_unstemmed | Nanosystems for modulation of immune responses in periodontal therapy: a mini-review |
| title_short | Nanosystems for modulation of immune responses in periodontal therapy: a mini-review |
| title_sort | nanosystems for modulation of immune responses in periodontal therapy a mini review |
| topic | nanotechnology immunomodulation nanosystems nanomedicine periodontitis therapy |
| url | https://www.frontiersin.org/articles/10.3389/fdmed.2024.1509775/full |
| work_keys_str_mv | AT anirudhbacharya nanosystemsformodulationofimmuneresponsesinperiodontaltherapyaminireview AT ushahegde nanosystemsformodulationofimmuneresponsesinperiodontaltherapyaminireview AT swethaacharya nanosystemsformodulationofimmuneresponsesinperiodontaltherapyaminireview |