ASF1B promotes gastric cancer progression by modulating H2AC20 and activating PI3K/AKT and ERK1/2 pathways

ASF1B promotes gastric cancer progression by modulating H2AC20 and activating PI3K/AKT and ERK1/2 pathways

BackgroundGastric cancer (GC) ranks among the most prevalent malignant neoplasms globally and is associated with a significant mortality rate. Despite the availability of various therapeutic interventions for GC, the overall prognosis for this disease remains unfavorable. This can be attributed to s...

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Bibliographic Details
Main Authors: Mengyuan Zhao, Junchang Zhang, Yanjun He, Chongge You
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
gastric cancer
AFS1B
H2AC20
PI3K/AKT
ERK1/2
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1533257/full
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