DOLPHIN advances single-cell transcriptomics beyond gene level by leveraging exon and junction reads

Abstract The advent of single-cell sequencing has revolutionized the study of cellular dynamics, providing unprecedented resolution into the molecular states and heterogeneity of individual cells. However, the rich potential of exon-level information and junction reads within single cells remains un...

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Bibliographic Details
Main Authors: Kailu Song, Yumin Zheng, Bowen Zhao, David H. Eidelman, Jian Tang, Jun Ding
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61580-w
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