Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c Mice
The goal of this study was to determine the effect of topical Emu oil on the healing of burn wounds and hair follicle restoration in superficial II-degree burns in the skin of Balb/c mice. Thirty-two male Balb/c mice with burns on the back of the neck were divided into two groups: The Emu oil group...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/6419216 |
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| author | Mohammad Afshar Reza Ghaderi Mahmoud Zardast Parvin Delshad |
| author_facet | Mohammad Afshar Reza Ghaderi Mahmoud Zardast Parvin Delshad |
| author_sort | Mohammad Afshar |
| collection | DOAJ |
| description | The goal of this study was to determine the effect of topical Emu oil on the healing of burn wounds and hair follicle restoration in superficial II-degree burns in the skin of Balb/c mice. Thirty-two male Balb/c mice with burns on the back of the neck were divided into two groups: The Emu oil group received topical Emu oil twice daily, whereas the control was left untreated. Skin biopsies were obtained on days 4, 7, 10, and 14 of the experiment. Then the specimens were viewed with Olympus SZX research microscope. The Emu oil treated burns were found to heal more slowly and inflammation lasted longer in this group. The number of hair follicles in the margins of the wounds increased through time in the Emu oil group compared to the control group. Also, the hair follicles in the Emu oil group were in several layers and seemed to be more active and mature. Moreover, Emu oil had a positive effect on fibrogenesis and synthesis of collagen. The findings indicate that although Emu oil delays the healing process, it has a positive effect on wound healing and it increases the number of hair follicles in the margins of the wound. |
| format | Article |
| id | doaj-art-3b6e1b1e219241c490adee5158785350 |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-3b6e1b1e219241c490adee51587853502025-02-03T05:48:02ZengWileyDermatology Research and Practice1687-61051687-61132016-01-01201610.1155/2016/64192166419216Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c MiceMohammad Afshar0Reza Ghaderi1Mahmoud Zardast2Parvin Delshad3Department of Anatomy, Faculty of Medicine, Birjand University of Medical Sciences, Moallem Street, Birjand 9717735338, IranDepartment of Dermatology, Faculty of Medicine, Birjand University of Medical Sciences, Moallem Street, Birjand 9717735338, IranFaculty of Medicine, Birjand University of Medical Sciences, Moallem Street, Birjand 9717735338, IranFaculty of Medicine, Birjand University of Medical Sciences, Moallem Street, Birjand 9717735338, IranThe goal of this study was to determine the effect of topical Emu oil on the healing of burn wounds and hair follicle restoration in superficial II-degree burns in the skin of Balb/c mice. Thirty-two male Balb/c mice with burns on the back of the neck were divided into two groups: The Emu oil group received topical Emu oil twice daily, whereas the control was left untreated. Skin biopsies were obtained on days 4, 7, 10, and 14 of the experiment. Then the specimens were viewed with Olympus SZX research microscope. The Emu oil treated burns were found to heal more slowly and inflammation lasted longer in this group. The number of hair follicles in the margins of the wounds increased through time in the Emu oil group compared to the control group. Also, the hair follicles in the Emu oil group were in several layers and seemed to be more active and mature. Moreover, Emu oil had a positive effect on fibrogenesis and synthesis of collagen. The findings indicate that although Emu oil delays the healing process, it has a positive effect on wound healing and it increases the number of hair follicles in the margins of the wound.http://dx.doi.org/10.1155/2016/6419216 |
| spellingShingle | Mohammad Afshar Reza Ghaderi Mahmoud Zardast Parvin Delshad Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c Mice Dermatology Research and Practice |
| title | Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c Mice |
| title_full | Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c Mice |
| title_fullStr | Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c Mice |
| title_full_unstemmed | Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c Mice |
| title_short | Effects of Topical Emu Oil on Burn Wounds in the Skin of Balb/c Mice |
| title_sort | effects of topical emu oil on burn wounds in the skin of balb c mice |
| url | http://dx.doi.org/10.1155/2016/6419216 |
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