Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin

Objectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU...

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Main Authors: Milagros Cruz, Ana M. Fernández-Alonso, Isabel Rodríguez, Loreto Garrigosa, Africa Caño, Pilar Carretero, Amelia Vizcaíno, Amanda Rocío Gonzalez-Ramirez
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2011/548327
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author Milagros Cruz
Ana M. Fernández-Alonso
Isabel Rodríguez
Loreto Garrigosa
Africa Caño
Pilar Carretero
Amelia Vizcaíno
Amanda Rocío Gonzalez-Ramirez
author_facet Milagros Cruz
Ana M. Fernández-Alonso
Isabel Rodríguez
Loreto Garrigosa
Africa Caño
Pilar Carretero
Amelia Vizcaíno
Amanda Rocío Gonzalez-Ramirez
author_sort Milagros Cruz
collection DOAJ
description Objectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU bemiparin once daily for 5 days or 3500 IU bemiparin once daily for 10 days. Results. There was one case of pulmonary embolism (first day following cesarean). An additional risk factor was present in 98.52% of the women, most frequently emergency cesarean, anemia, or obesity. The only risk factors for thromboembolic disease significantly related to pulmonary thromboembolism were placental abruption and prematurity. There were no differences in thromboembolic events among the two thromboprophylaxis regimens. Conclusions. Cesarean-related thromboembolic events were reduced in our study population due to the thromboprophylactic measures taken. Thromboprophylaxis with 3500 IU bemiparin once daily for 5 days following cesarean was sufficient to avoid thromboembolic events.
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institution Kabale University
issn 1687-9589
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language English
publishDate 2011-01-01
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series Obstetrics and Gynecology International
spelling doaj-art-3b690bbbfa9b4a28af50ebf1d0fff8c12025-08-20T03:55:36ZengWileyObstetrics and Gynecology International1687-95891687-95972011-01-01201110.1155/2011/548327548327Postcesarean Thromboprophylaxis with Two Different Regimens of BemiparinMilagros Cruz0Ana M. Fernández-Alonso1Isabel Rodríguez2Loreto Garrigosa3Africa Caño4Pilar Carretero5Amelia Vizcaíno6Amanda Rocío Gonzalez-Ramirez7Obstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObstetrics and Gynecology Department, San Cecilio University Hospital, Avenida Madrid No. 16, 18012 Granada, SpainObjectives. To compare the effectiveness of postcesarean thromboprophylaxis with two different regimens of bemiparin. Material and Methods. The study included 646 women with cesarean delivery in our hospital within a 1-year period, randomly assigned to one of two groups for prophylaxis with 3500 IU bemiparin once daily for 5 days or 3500 IU bemiparin once daily for 10 days. Results. There was one case of pulmonary embolism (first day following cesarean). An additional risk factor was present in 98.52% of the women, most frequently emergency cesarean, anemia, or obesity. The only risk factors for thromboembolic disease significantly related to pulmonary thromboembolism were placental abruption and prematurity. There were no differences in thromboembolic events among the two thromboprophylaxis regimens. Conclusions. Cesarean-related thromboembolic events were reduced in our study population due to the thromboprophylactic measures taken. Thromboprophylaxis with 3500 IU bemiparin once daily for 5 days following cesarean was sufficient to avoid thromboembolic events.http://dx.doi.org/10.1155/2011/548327
spellingShingle Milagros Cruz
Ana M. Fernández-Alonso
Isabel Rodríguez
Loreto Garrigosa
Africa Caño
Pilar Carretero
Amelia Vizcaíno
Amanda Rocío Gonzalez-Ramirez
Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
Obstetrics and Gynecology International
title Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_full Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_fullStr Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_full_unstemmed Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_short Postcesarean Thromboprophylaxis with Two Different Regimens of Bemiparin
title_sort postcesarean thromboprophylaxis with two different regimens of bemiparin
url http://dx.doi.org/10.1155/2011/548327
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