Exploring protein - protein interaction in cell physiology by reviewing the role of dynein-dynactin interaction as a representative example

Protein-protein interactions are essential for the normal function of cells and are involved in various cellular processes. These interactions can occur through a variety of mechanisms, including hydrogen bonding, ionic interactions, and hydrophobic interactions. Changes in protein-protein interacti...

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Bibliographic Details
Main Author: Neelabh DATTA
Format: Article
Language:English
Published: Cluj University Press 2023-06-01
Series:Studia Universitatis Babeș-Bolyai. Biologia
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Online Access:https://studiabiologia.reviste.ubbcluj.ro/index.php/studiabio/article/view/122
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Summary:Protein-protein interactions are essential for the normal function of cells and are involved in various cellular processes. These interactions can occur through a variety of mechanisms, including hydrogen bonding, ionic interactions, and hydrophobic interactions. Changes in protein-protein interactions can alter the normal function of the cell and lead to various diseases. Understanding protein-protein interactions is important for the development of therapeutic approaches targeting these interactions for the treatment of diseases. In this article, I will discuss the role of protein-protein interactions in normal cellular function, the consequences of changes in these interactions, and the importance and significance of understanding these interactions by using the example of dynein-dynactin. Article history: Received: 27 February 2023; Revised: 23 March 2023; Accepted: 24 May 2023; Available online: 30 June 2023.
ISSN:2065-9512