Exploring the Role of mRNA Methylation in Insect Biology and Resistance
RNA methylation, characterized by modifications such as <i>N</i><sup>6</sup>-methyladenosine, 5-methylcytosine, and <i>N</i><sup>1</sup>-methyladenosine plays a crucial role in post-transcriptional gene regulation across diverse biological systems. Whi...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-04-01
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| Series: | Insects |
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| Online Access: | https://www.mdpi.com/2075-4450/16/5/463 |
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| author | Jiayang Zhang Luobin Lin Botian Huang Huoxi Liu Huaqin Li Wenmei Wu |
| author_facet | Jiayang Zhang Luobin Lin Botian Huang Huoxi Liu Huaqin Li Wenmei Wu |
| author_sort | Jiayang Zhang |
| collection | DOAJ |
| description | RNA methylation, characterized by modifications such as <i>N</i><sup>6</sup>-methyladenosine, 5-methylcytosine, and <i>N</i><sup>1</sup>-methyladenosine plays a crucial role in post-transcriptional gene regulation across diverse biological systems. While research on RNA methylation has predominantly focused on mammals, particularly its roles in epigenetic regulation and cancer biology, recent studies in insects have begun to explore their extensive functions in insect physiology. This review examines the mechanisms by which RNA methylation regulates growth, development, reproduction, environmental adaptation, and immune response in insects, providing insights into the biological characteristics of these organisms without prematurely speculating on pest control strategies. It aims to offer valuable insights into the role of RNA methylation in insect biology and resistance. |
| format | Article |
| id | doaj-art-3b628b4047b4477aaf91ba3c486ee8d0 |
| institution | Kabale University |
| issn | 2075-4450 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Insects |
| spelling | doaj-art-3b628b4047b4477aaf91ba3c486ee8d02025-08-20T03:48:01ZengMDPI AGInsects2075-44502025-04-0116546310.3390/insects16050463Exploring the Role of mRNA Methylation in Insect Biology and ResistanceJiayang Zhang0Luobin Lin1Botian Huang2Huoxi Liu3Huaqin Li4Wenmei Wu5Guangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Centerof Topical Precise Drug Delivery System, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Centerof Topical Precise Drug Delivery System, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Centerof Topical Precise Drug Delivery System, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, ChinaGuangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Centerof Topical Precise Drug Delivery System, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, ChinaSchool of Health Sciences, Guangzhou Xinhua University, Guangzhou 510520, ChinaGuangdong Provincial Key Laboratory of Advanced Drug Delivery, Guangdong Provincial Engineering Centerof Topical Precise Drug Delivery System, School of Life Sciences and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou 510006, ChinaRNA methylation, characterized by modifications such as <i>N</i><sup>6</sup>-methyladenosine, 5-methylcytosine, and <i>N</i><sup>1</sup>-methyladenosine plays a crucial role in post-transcriptional gene regulation across diverse biological systems. While research on RNA methylation has predominantly focused on mammals, particularly its roles in epigenetic regulation and cancer biology, recent studies in insects have begun to explore their extensive functions in insect physiology. This review examines the mechanisms by which RNA methylation regulates growth, development, reproduction, environmental adaptation, and immune response in insects, providing insights into the biological characteristics of these organisms without prematurely speculating on pest control strategies. It aims to offer valuable insights into the role of RNA methylation in insect biology and resistance.https://www.mdpi.com/2075-4450/16/5/463epigenetic modifications<i>N</i><sup>6</sup>-methyladenosine (m<sup>6</sup>A)5-methylcytosine (m<sup>5</sup>C)<i>N</i><sup>1</sup>-methyladenosine (m<sup>1</sup>A)insectspest control strategies |
| spellingShingle | Jiayang Zhang Luobin Lin Botian Huang Huoxi Liu Huaqin Li Wenmei Wu Exploring the Role of mRNA Methylation in Insect Biology and Resistance Insects epigenetic modifications <i>N</i><sup>6</sup>-methyladenosine (m<sup>6</sup>A) 5-methylcytosine (m<sup>5</sup>C) <i>N</i><sup>1</sup>-methyladenosine (m<sup>1</sup>A) insects pest control strategies |
| title | Exploring the Role of mRNA Methylation in Insect Biology and Resistance |
| title_full | Exploring the Role of mRNA Methylation in Insect Biology and Resistance |
| title_fullStr | Exploring the Role of mRNA Methylation in Insect Biology and Resistance |
| title_full_unstemmed | Exploring the Role of mRNA Methylation in Insect Biology and Resistance |
| title_short | Exploring the Role of mRNA Methylation in Insect Biology and Resistance |
| title_sort | exploring the role of mrna methylation in insect biology and resistance |
| topic | epigenetic modifications <i>N</i><sup>6</sup>-methyladenosine (m<sup>6</sup>A) 5-methylcytosine (m<sup>5</sup>C) <i>N</i><sup>1</sup>-methyladenosine (m<sup>1</sup>A) insects pest control strategies |
| url | https://www.mdpi.com/2075-4450/16/5/463 |
| work_keys_str_mv | AT jiayangzhang exploringtheroleofmrnamethylationininsectbiologyandresistance AT luobinlin exploringtheroleofmrnamethylationininsectbiologyandresistance AT botianhuang exploringtheroleofmrnamethylationininsectbiologyandresistance AT huoxiliu exploringtheroleofmrnamethylationininsectbiologyandresistance AT huaqinli exploringtheroleofmrnamethylationininsectbiologyandresistance AT wenmeiwu exploringtheroleofmrnamethylationininsectbiologyandresistance |