Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children
ObjectiveThe aim of this study is to evaluate the efficacy and safety of ADO-II percutaneous occlusion and traditional open-chest surgery for treating doubly committed subarterial ventricular septal defect (dcVSD) in children.MethodsThe clinical data of 151 children with dcVSD treated at Chongqing M...
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Frontiers Media S.A.
2025-04-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| author | Bei Tan Mi Li Mi Li Mi Li Mi Li Mi Li Mi Li Mi Li Kaijun Zhang Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Qiuyue Ao Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang |
| author_facet | Bei Tan Mi Li Mi Li Mi Li Mi Li Mi Li Mi Li Mi Li Kaijun Zhang Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Qiuyue Ao Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang |
| author_sort | Bei Tan |
| collection | DOAJ |
| description | ObjectiveThe aim of this study is to evaluate the efficacy and safety of ADO-II percutaneous occlusion and traditional open-chest surgery for treating doubly committed subarterial ventricular septal defect (dcVSD) in children.MethodsThe clinical data of 151 children with dcVSD treated at Chongqing Medical University Affiliated Children's Hospital between July 2019 and May 2024 were retrospectively analyzed. Patients were divided into a transcatheter group (percutaneous occlusion) and a surgical group (open-chest repair) on the basis of the treatment method used. Key evaluation metrics included procedural success rates, complication rates, and perioperative management parameters.ResultsOcclusion technical success was 94.9% (37/39) in the interventional sample of 39 patients. The 112 surgical patients had a 100% technical success rate. Three interventional patients had sinus rhythm before discharge, and 2 of 18 surgical patients had residual right bundle branch block at the last follow-up. The mild aortic valve prolapse of 115 individuals (76.2%) improved to varied degrees postoperatively. Of 96 individuals with preoperative aortic regurgitation, 83 exhibited no change, 49 improved, 17 developed new regurgitation, and two worsened. The two groups differed significantly in postoperative hospital stay, time to independent ambulation, operative time, mechanical ventilation, blooding amount, Blood transfusion volume, Fever within 72 h after operation, pulmonary infections, intravenous nutrition, antibiotic use, and hospitalization cost (all p < 0.05). There no serious problems were recorded the transcatheter group, including device dislodgement, cardiac or vascular perforation, death, or hemolysis. In the surgical group, one patient had residual shunting reoperation and another had infective endocarditis.ConclusionChildren with dcVSD can recover faster and safer using ADO-II percutaneous occlusion, which is minimally invasive and inexpensive. It can be the first-line treatment for selected patients. |
| format | Article |
| id | doaj-art-3b54f04b61ba4f04b61d55dfb248bc3f |
| institution | OA Journals |
| issn | 2297-055X |
| language | English |
| publishDate | 2025-04-01 |
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| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj-art-3b54f04b61ba4f04b61d55dfb248bc3f2025-08-20T02:12:19ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-04-011210.3389/fcvm.2025.15417961541796Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in childrenBei Tan0Mi Li1Mi Li2Mi Li3Mi Li4Mi Li5Mi Li6Mi Li7Kaijun Zhang8Xue Zhou9Xue Zhou10Xue Zhou11Xue Zhou12Xue Zhou13Xue Zhou14Xue Zhou15Qiuyue Ao16Dan Yin17Dan Yin18Dan Yin19Dan Yin20Dan Yin21Dan Yin22Dan Yin23Zhenli Cheng24Zhenli Cheng25Zhenli Cheng26Zhenli Cheng27Zhenli Cheng28Zhenli Cheng29Zhenli Cheng30Ping Xiang31Ping Xiang32Ping Xiang33Ping Xiang34Ping Xiang35Ping Xiang36Ping Xiang37Children’s Hospital of Chongqing Medical University, Chongqing, ChinaChildren’s Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaKey Laboratory of Children’s Important Organ Development and Diseases, Chongqing Municipal Health Commission, Chongqing, ChinaNational Clinical Key Cardiovascular Specialty, Chongqing, ChinaChildren’s Hospital of Chongqing Medical University, Chongqing, ChinaChildren’s Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaKey Laboratory of Children’s Important Organ Development and Diseases, Chongqing Municipal Health Commission, Chongqing, ChinaNational Clinical Key Cardiovascular Specialty, Chongqing, ChinaChildren’s Hospital of Chongqing Medical University, Chongqing, ChinaChildren’s Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaKey Laboratory of Children’s Important Organ Development and Diseases, Chongqing Municipal Health Commission, Chongqing, ChinaNational Clinical Key Cardiovascular Specialty, Chongqing, ChinaChildren’s Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaKey Laboratory of Children’s Important Organ Development and Diseases, Chongqing Municipal Health Commission, Chongqing, ChinaNational Clinical Key Cardiovascular Specialty, Chongqing, ChinaChildren’s Hospital of Chongqing Medical University, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaKey Laboratory of Children’s Important Organ Development and Diseases, Chongqing Municipal Health Commission, Chongqing, ChinaNational Clinical Key Cardiovascular Specialty, Chongqing, ChinaObjectiveThe aim of this study is to evaluate the efficacy and safety of ADO-II percutaneous occlusion and traditional open-chest surgery for treating doubly committed subarterial ventricular septal defect (dcVSD) in children.MethodsThe clinical data of 151 children with dcVSD treated at Chongqing Medical University Affiliated Children's Hospital between July 2019 and May 2024 were retrospectively analyzed. Patients were divided into a transcatheter group (percutaneous occlusion) and a surgical group (open-chest repair) on the basis of the treatment method used. Key evaluation metrics included procedural success rates, complication rates, and perioperative management parameters.ResultsOcclusion technical success was 94.9% (37/39) in the interventional sample of 39 patients. The 112 surgical patients had a 100% technical success rate. Three interventional patients had sinus rhythm before discharge, and 2 of 18 surgical patients had residual right bundle branch block at the last follow-up. The mild aortic valve prolapse of 115 individuals (76.2%) improved to varied degrees postoperatively. Of 96 individuals with preoperative aortic regurgitation, 83 exhibited no change, 49 improved, 17 developed new regurgitation, and two worsened. The two groups differed significantly in postoperative hospital stay, time to independent ambulation, operative time, mechanical ventilation, blooding amount, Blood transfusion volume, Fever within 72 h after operation, pulmonary infections, intravenous nutrition, antibiotic use, and hospitalization cost (all p < 0.05). There no serious problems were recorded the transcatheter group, including device dislodgement, cardiac or vascular perforation, death, or hemolysis. In the surgical group, one patient had residual shunting reoperation and another had infective endocarditis.ConclusionChildren with dcVSD can recover faster and safer using ADO-II percutaneous occlusion, which is minimally invasive and inexpensive. It can be the first-line treatment for selected patients.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1541796/fulldoubly committed subarterial ventricular septal defectamplatzer duct occluder-IIinterventional cardiologychildrensurgical repair |
| spellingShingle | Bei Tan Mi Li Mi Li Mi Li Mi Li Mi Li Mi Li Mi Li Kaijun Zhang Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Xue Zhou Qiuyue Ao Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Dan Yin Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Zhenli Cheng Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children Frontiers in Cardiovascular Medicine doubly committed subarterial ventricular septal defect amplatzer duct occluder-II interventional cardiology children surgical repair |
| title | Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children |
| title_full | Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children |
| title_fullStr | Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children |
| title_full_unstemmed | Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children |
| title_short | Comparison of ADO-II percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children |
| title_sort | comparison of ado ii percutaneous occlusion and traditional surgery in the treatment of doubly committed subarterial ventricular septal defects in children |
| topic | doubly committed subarterial ventricular septal defect amplatzer duct occluder-II interventional cardiology children surgical repair |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1541796/full |
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