Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging Diagnosis
A 68-year-old patient presented with persistent hemoptysis and weight loss. A CT scan showing diffuse bilateral ground-glass opacities and nodules was followed by bronchoscopy. While diffuse alveolar hemorrhage (DAH) could be seen, specimens obtained during bronchoscopy did not provide conclusive hi...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2023/5553209 |
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| author | Felix Wuest Andreas Gebhardt Claudia Grosswendt Sergej Griff Antonina Zhilina Samantha Taber Jens Kollmeier Torsten T. Bauer |
| author_facet | Felix Wuest Andreas Gebhardt Claudia Grosswendt Sergej Griff Antonina Zhilina Samantha Taber Jens Kollmeier Torsten T. Bauer |
| author_sort | Felix Wuest |
| collection | DOAJ |
| description | A 68-year-old patient presented with persistent hemoptysis and weight loss. A CT scan showing diffuse bilateral ground-glass opacities and nodules was followed by bronchoscopy. While diffuse alveolar hemorrhage (DAH) could be seen, specimens obtained during bronchoscopy did not provide conclusive histological findings. The decision was made to conduct video-assisted wedge resection, after which histological examinations revealed the diagnosis of bifocal nodular manifestation of an epithelioid angiosarcoma in the lung. Being a rare entity even among sarcomas, these kinds of tumors can be primary lung tissue angiosarcomas or metastatic lesions with primaries in places like the skin, breast, and heart. Treatment usually includes chemotherapy, but prognosis remains grim. This case highlights that in DAH, uncommon causes should be considered, and sufficient probe gathering is the key to early diagnosis and treatment. |
| format | Article |
| id | doaj-art-3b4ac09fbec74fa2880d01f7f8481206 |
| institution | Kabale University |
| issn | 2090-6854 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-3b4ac09fbec74fa2880d01f7f84812062025-08-20T03:55:36ZengWileyCase Reports in Pulmonology2090-68542023-01-01202310.1155/2023/5553209Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging DiagnosisFelix Wuest0Andreas Gebhardt1Claudia Grosswendt2Sergej Griff3Antonina Zhilina4Samantha Taber5Jens Kollmeier6Torsten T. Bauer7Department of PneumologyDepartment of PneumologyInstitute of Diagnostic and Interventional RadiologyInstitute of PathologyInstitute of PathologyDepartment of Thoracic SurgeryDepartment of PneumologyDepartment of PneumologyA 68-year-old patient presented with persistent hemoptysis and weight loss. A CT scan showing diffuse bilateral ground-glass opacities and nodules was followed by bronchoscopy. While diffuse alveolar hemorrhage (DAH) could be seen, specimens obtained during bronchoscopy did not provide conclusive histological findings. The decision was made to conduct video-assisted wedge resection, after which histological examinations revealed the diagnosis of bifocal nodular manifestation of an epithelioid angiosarcoma in the lung. Being a rare entity even among sarcomas, these kinds of tumors can be primary lung tissue angiosarcomas or metastatic lesions with primaries in places like the skin, breast, and heart. Treatment usually includes chemotherapy, but prognosis remains grim. This case highlights that in DAH, uncommon causes should be considered, and sufficient probe gathering is the key to early diagnosis and treatment.http://dx.doi.org/10.1155/2023/5553209 |
| spellingShingle | Felix Wuest Andreas Gebhardt Claudia Grosswendt Sergej Griff Antonina Zhilina Samantha Taber Jens Kollmeier Torsten T. Bauer Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging Diagnosis Case Reports in Pulmonology |
| title | Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging Diagnosis |
| title_full | Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging Diagnosis |
| title_fullStr | Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging Diagnosis |
| title_full_unstemmed | Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging Diagnosis |
| title_short | Diffuse Alveolar Hemorrhage Associated with Epithelioid Angiosarcoma of the Lung: A Challenging Diagnosis |
| title_sort | diffuse alveolar hemorrhage associated with epithelioid angiosarcoma of the lung a challenging diagnosis |
| url | http://dx.doi.org/10.1155/2023/5553209 |
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