ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway

ESAT-6 protein suppresses allograft rejection by inducing CD4+Foxp3+ regulatory T cells through IκBα/cRel pathway

BackgroundMaintenance immunosuppression is required for suppression of alloimmunity or allograft rejection. However, continuous use of immunosuppressants may lead to various side effects, necessitating the use of alternative immunosuppressive drugs. The early secreted antigenic target of 6 kDa (ESAT...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaofei Huang, Yuqun Zeng, Jingru Lin, Huazhen Liu, Chun-Ling Liang, Yuchao Chen, Feifei Qiu, Jonathan S. Bromberg, Zhenhua Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
transplantation
ESAT-6
alloimmunity
regulatory T cell (Treg)
immunoregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1529226/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items