Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community Hospital

Bezoars are indigestible masses that can cause gastrointestinal complications such as obstructions and perforations. We report the case of a 60-year-old man with a history of type 2 diabetes mellitus and duodenal ulcer surgery. The patient developed a large gastric phytobezoar that caused persistent...

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Main Authors: Jaewon Song, Dong Yeol Shin
Format: Article
Language:English
Published: Korean College of Helicobacter and Upper Gastrointestinal Research 2025-03-01
Series:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
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Online Access:http://helicojournal.org/upload/pdf/kjhugr-2024-0066.pdf
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author Jaewon Song
Dong Yeol Shin
author_facet Jaewon Song
Dong Yeol Shin
author_sort Jaewon Song
collection DOAJ
description Bezoars are indigestible masses that can cause gastrointestinal complications such as obstructions and perforations. We report the case of a 60-year-old man with a history of type 2 diabetes mellitus and duodenal ulcer surgery. The patient developed a large gastric phytobezoar that caused persistent dyspepsia and epigastric pain. Upper endoscopy confirmed a 10-cm phytobezoar and a 1.5-cm active ulcer at the gastric angle. To soften the bezoar, Coca-Cola and cellulase were administered to the patient. This treatment significantly reduced the bezoar’s hardness, permitting its successful endoscopic fragmentation using conventional devices. Over three endoscopic sessions, the bezoar was fragmented into pieces smaller than 1 cm and removed; thereafter, the gastric ulcer healed completely. This case illustrates the effectiveness of combining the actions of Coca-Cola and cellulase with endoscopic methods to treat large bezoars, providing an alternative to surgical approaches in community healthcare settings.
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language English
publishDate 2025-03-01
publisher Korean College of Helicobacter and Upper Gastrointestinal Research
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series The Korean Journal of Helicobacter and Upper Gastrointestinal Research
spelling doaj-art-3b446535fef0434fbb8e025d655cf3d32025-08-20T03:14:39ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312025-03-01251737710.7704/kjhugr.2024.0066895Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community HospitalJaewon Song0Dong Yeol Shin1 Department of Internal Medicine, Namyangju Yang Hospital, Namyangju, Korea Department of Internal Medicine, Namyangju Yang Hospital, Namyangju, KoreaBezoars are indigestible masses that can cause gastrointestinal complications such as obstructions and perforations. We report the case of a 60-year-old man with a history of type 2 diabetes mellitus and duodenal ulcer surgery. The patient developed a large gastric phytobezoar that caused persistent dyspepsia and epigastric pain. Upper endoscopy confirmed a 10-cm phytobezoar and a 1.5-cm active ulcer at the gastric angle. To soften the bezoar, Coca-Cola and cellulase were administered to the patient. This treatment significantly reduced the bezoar’s hardness, permitting its successful endoscopic fragmentation using conventional devices. Over three endoscopic sessions, the bezoar was fragmented into pieces smaller than 1 cm and removed; thereafter, the gastric ulcer healed completely. This case illustrates the effectiveness of combining the actions of Coca-Cola and cellulase with endoscopic methods to treat large bezoars, providing an alternative to surgical approaches in community healthcare settings.http://helicojournal.org/upload/pdf/kjhugr-2024-0066.pdfbezoarendoscopycellulase
spellingShingle Jaewon Song
Dong Yeol Shin
Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community Hospital
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
bezoar
endoscopy
cellulase
title Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community Hospital
title_full Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community Hospital
title_fullStr Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community Hospital
title_full_unstemmed Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community Hospital
title_short Treatment of a Large Gastric Phytobezoar With Coca-Cola, Cellulase, and Endoscopic Fragmentation in a Community Hospital
title_sort treatment of a large gastric phytobezoar with coca cola cellulase and endoscopic fragmentation in a community hospital
topic bezoar
endoscopy
cellulase
url http://helicojournal.org/upload/pdf/kjhugr-2024-0066.pdf
work_keys_str_mv AT jaewonsong treatmentofalargegastricphytobezoarwithcocacolacellulaseandendoscopicfragmentationinacommunityhospital
AT dongyeolshin treatmentofalargegastricphytobezoarwithcocacolacellulaseandendoscopicfragmentationinacommunityhospital