Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved]
Background Lung cancer is the leading cause of cancer-related mortality worldwide. Low-dose CT (LDCT) lung cancer screening (LCS) reduces lung cancer-specific mortality by 20%, yet participation remains low, often below 15%, compared with 60–75% for other cancer screening programmes. Barriers such a...
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F1000 Research Ltd
2025-06-01
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| Online Access: | https://hrbopenresearch.org/articles/8-71/v1 |
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| author | Tytti Sarkeala Patrick Redmond Bethany Cushing Benjamin Jacob XinYi Low Ildiko Horvath Sam McGlynn Martina Vranka |
| author_facet | Tytti Sarkeala Patrick Redmond Bethany Cushing Benjamin Jacob XinYi Low Ildiko Horvath Sam McGlynn Martina Vranka |
| author_sort | Tytti Sarkeala |
| collection | DOAJ |
| description | Background Lung cancer is the leading cause of cancer-related mortality worldwide. Low-dose CT (LDCT) lung cancer screening (LCS) reduces lung cancer-specific mortality by 20%, yet participation remains low, often below 15%, compared with 60–75% for other cancer screening programmes. Barriers such as limited accessibility, stigma, fear of diagnosis, and misconceptions contribute to poor uptake, particularly among high-risk groups, including heavy smokers, ethnic minorities, and individuals from lower socioeconomic backgrounds. Various recruitment strategies—such as personalised invitations, media campaigns, and primary care referrals—have been implemented, but their effectiveness across different populations remains unclear. This umbrella review will synthesise evidence from systematic reviews to identify the most effective recruitment strategies for improving LCS participation. Methods This umbrella review will follow Joanna Briggs Institute guidelines and the PRIOR reporting framework. A systematic search of PubMed, Embase, Scopus, Web of Science, Cochrane Library, and systematic review registries will identify systematic reviews published before 31 October 2024. Eligible reviews must evaluate LCS recruitment strategies and report on at least one of the following: population reach, screening up take, adherence, patient experience, or implementation barriers. Quality will be assessed using AMSTAR 2, and overlapping primary studies will be mapped to prevent duplication. A narrative synthesis will categorise recruitment strategies, and a qualitative effectiveness ranking will summarise key findings. Implications Findings will inform LCS recruitment strategies in Europe, contributing to the EU4Health-funded EUCanScreen programme. This review will support efforts to improve uptake, reduce disparities, and enhance early detection and survival outcomes of lung cancer. |
| format | Article |
| id | doaj-art-3b33f682b99a4702b47e26c7b372df74 |
| institution | Kabale University |
| issn | 2515-4826 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | HRB Open Research |
| spelling | doaj-art-3b33f682b99a4702b47e26c7b372df742025-08-24T01:00:01ZengF1000 Research LtdHRB Open Research2515-48262025-06-01810.12688/hrbopenres.14160.115572Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved]Tytti Sarkeala0Patrick Redmond1https://orcid.org/0000-0002-3929-2018Bethany Cushing2https://orcid.org/0009-0003-1896-5732Benjamin Jacob3https://orcid.org/0000-0003-1119-064XXinYi Low4https://orcid.org/0009-0006-7987-4967Ildiko Horvath5Sam McGlynn6Martina Vranka7Finnish Cancer Registry, Helsinki, 00500, FinlandRoyal College of Surgeons in Ireland Department of General Practice, Dublin, Leinster, IrelandRoyal College of Surgeons in Ireland School of Medicine, Dublin, Leinster, IrelandRoyal College of Surgeons in Ireland Department of General Practice, Dublin, Leinster, IrelandRoyal College of Surgeons in Ireland School of Medicine, Dublin, Leinster, IrelandNational Koranyi Institute for Pulmonology, Budapest, HungaryRoyal College of Surgeons in Ireland Department of General Practice, Dublin, Leinster, IrelandDivision of Radiotherapy, Institute of Oncology Ljubljana, Ljubljana, SloveniaBackground Lung cancer is the leading cause of cancer-related mortality worldwide. Low-dose CT (LDCT) lung cancer screening (LCS) reduces lung cancer-specific mortality by 20%, yet participation remains low, often below 15%, compared with 60–75% for other cancer screening programmes. Barriers such as limited accessibility, stigma, fear of diagnosis, and misconceptions contribute to poor uptake, particularly among high-risk groups, including heavy smokers, ethnic minorities, and individuals from lower socioeconomic backgrounds. Various recruitment strategies—such as personalised invitations, media campaigns, and primary care referrals—have been implemented, but their effectiveness across different populations remains unclear. This umbrella review will synthesise evidence from systematic reviews to identify the most effective recruitment strategies for improving LCS participation. Methods This umbrella review will follow Joanna Briggs Institute guidelines and the PRIOR reporting framework. A systematic search of PubMed, Embase, Scopus, Web of Science, Cochrane Library, and systematic review registries will identify systematic reviews published before 31 October 2024. Eligible reviews must evaluate LCS recruitment strategies and report on at least one of the following: population reach, screening up take, adherence, patient experience, or implementation barriers. Quality will be assessed using AMSTAR 2, and overlapping primary studies will be mapped to prevent duplication. A narrative synthesis will categorise recruitment strategies, and a qualitative effectiveness ranking will summarise key findings. Implications Findings will inform LCS recruitment strategies in Europe, contributing to the EU4Health-funded EUCanScreen programme. This review will support efforts to improve uptake, reduce disparities, and enhance early detection and survival outcomes of lung cancer.https://hrbopenresearch.org/articles/8-71/v1Umbrella review; Early detection of cancer; Cancer screening; Lung cancer; participation; Primary careeng |
| spellingShingle | Tytti Sarkeala Patrick Redmond Bethany Cushing Benjamin Jacob XinYi Low Ildiko Horvath Sam McGlynn Martina Vranka Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved] HRB Open Research Umbrella review; Early detection of cancer; Cancer screening; Lung cancer; participation; Primary care eng |
| title | Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved] |
| title_full | Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved] |
| title_fullStr | Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved] |
| title_full_unstemmed | Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved] |
| title_short | Recruitment Strategies for Lung Cancer Screening: An Umbrella Review Protocol [version 1; peer review: 2 approved] |
| title_sort | recruitment strategies for lung cancer screening an umbrella review protocol version 1 peer review 2 approved |
| topic | Umbrella review; Early detection of cancer; Cancer screening; Lung cancer; participation; Primary care eng |
| url | https://hrbopenresearch.org/articles/8-71/v1 |
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