Quantitative Approach to Explore Regulatory T Cell Activity in Immuno-Oncology

Quantitative Approach to Explore Regulatory T Cell Activity in Immuno-Oncology

The failure of immunotherapies in cancer patients is being widely studied due to the complexities present in the tumor microenvironment (TME), where regulatory T cells (Treg) appear to actively participate in providing an immune escape mechanism for tumors. Therefore, therapies to specifically inhib...

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Bibliographic Details
Main Authors: Alejandro Serrano, Sara Zalba, Juan Jose Lasarte, Iñaki F. Troconiz, Natalia Riva, Maria J. Garrido
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
Treg cells
QSP model
immunotherapy
tumor growth dynamics
computational immune framework
Online Access:https://www.mdpi.com/1999-4923/16/11/1461
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