The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.

<h4>Background</h4>Despite recent decreases in HIV incidence in many sub-Saharan African countries, there is little evidence that specific behavioural interventions have led to a reduction in HIV among young people. Further and wider-scale decreases in HIV require better understanding of...

Full description

Saved in:
Bibliographic Details
Main Authors: Aoife M Doyle, Helen A Weiss, Kaballa Maganja, Saidi Kapiga, Sheena McCormack, Deborah Watson-Jones, John Changalucha, Richard J Hayes, David A Ross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0024866&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849727604602437632
author Aoife M Doyle
Helen A Weiss
Kaballa Maganja
Saidi Kapiga
Sheena McCormack
Deborah Watson-Jones
John Changalucha
Richard J Hayes
David A Ross
author_facet Aoife M Doyle
Helen A Weiss
Kaballa Maganja
Saidi Kapiga
Sheena McCormack
Deborah Watson-Jones
John Changalucha
Richard J Hayes
David A Ross
author_sort Aoife M Doyle
collection DOAJ
description <h4>Background</h4>Despite recent decreases in HIV incidence in many sub-Saharan African countries, there is little evidence that specific behavioural interventions have led to a reduction in HIV among young people. Further and wider-scale decreases in HIV require better understanding of when behaviour change occurs and why. The MEMA kwa Vijana adolescent sexual and reproductive health intervention has been implemented in rural Mwanza, Tanzania since 1999. A long-term evaluation in 2007/8 found that the intervention improved knowledge, attitudes to sex and some reported risk behaviours, but not HIV or HSV2 prevalence. The aim of this paper was to assess the differential impact of the intervention according to gender, age, marital status, number of years of exposure and time since last exposure to the intervention.<h4>Methods</h4>In 2007, a cross-sectional survey was conducted in the 20 trial communities among 13,814 young people (15-30 yrs) who had attended intervention or comparison schools between 1999 and 2002. Outcomes for which the intervention had an impact in 2001 or 2007 were included in this subgroup analysis. Data were analysed using cluster-level methods for stratified cluster-randomised trials, using interaction tests to determine if intervention impact differed by subgroup.<h4>Results</h4>Taking into account multiplicity of testing, concurrence with a priori hypotheses and consistency within the results no strong effect-modifiers emerged. Impact on pregnancy knowledge and reported attitudes to sex increased with years of exposure to high-quality intervention.<h4>Conclusions</h4>The desirable long-term impact of the MEMA kwa Vijana intervention did not vary greatly according to the subgroups examined. This suggests that the intervention can have an impact on a broad cross-section of young people in rural Mwanza.<h4>Trial registration</h4>ClinicalTrials.gov NCT00248469.
format Article
id doaj-art-3b24c0ad5cd6473c88f49232f6be481b
institution DOAJ
issn 1932-6203
language English
publishDate 2011-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj-art-3b24c0ad5cd6473c88f49232f6be481b2025-08-20T03:09:48ZengPublic Library of Science (PLoS)PLoS ONE1932-62032011-01-0169e2486610.1371/journal.pone.0024866The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.Aoife M DoyleHelen A WeissKaballa MaganjaSaidi KapigaSheena McCormackDeborah Watson-JonesJohn ChangaluchaRichard J HayesDavid A Ross<h4>Background</h4>Despite recent decreases in HIV incidence in many sub-Saharan African countries, there is little evidence that specific behavioural interventions have led to a reduction in HIV among young people. Further and wider-scale decreases in HIV require better understanding of when behaviour change occurs and why. The MEMA kwa Vijana adolescent sexual and reproductive health intervention has been implemented in rural Mwanza, Tanzania since 1999. A long-term evaluation in 2007/8 found that the intervention improved knowledge, attitudes to sex and some reported risk behaviours, but not HIV or HSV2 prevalence. The aim of this paper was to assess the differential impact of the intervention according to gender, age, marital status, number of years of exposure and time since last exposure to the intervention.<h4>Methods</h4>In 2007, a cross-sectional survey was conducted in the 20 trial communities among 13,814 young people (15-30 yrs) who had attended intervention or comparison schools between 1999 and 2002. Outcomes for which the intervention had an impact in 2001 or 2007 were included in this subgroup analysis. Data were analysed using cluster-level methods for stratified cluster-randomised trials, using interaction tests to determine if intervention impact differed by subgroup.<h4>Results</h4>Taking into account multiplicity of testing, concurrence with a priori hypotheses and consistency within the results no strong effect-modifiers emerged. Impact on pregnancy knowledge and reported attitudes to sex increased with years of exposure to high-quality intervention.<h4>Conclusions</h4>The desirable long-term impact of the MEMA kwa Vijana intervention did not vary greatly according to the subgroups examined. This suggests that the intervention can have an impact on a broad cross-section of young people in rural Mwanza.<h4>Trial registration</h4>ClinicalTrials.gov NCT00248469.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0024866&type=printable
spellingShingle Aoife M Doyle
Helen A Weiss
Kaballa Maganja
Saidi Kapiga
Sheena McCormack
Deborah Watson-Jones
John Changalucha
Richard J Hayes
David A Ross
The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
PLoS ONE
title The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
title_full The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
title_fullStr The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
title_full_unstemmed The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
title_short The long-term impact of the MEMA kwa Vijana adolescent sexual and reproductive health intervention: effect of dose and time since intervention exposure.
title_sort long term impact of the mema kwa vijana adolescent sexual and reproductive health intervention effect of dose and time since intervention exposure
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0024866&type=printable
work_keys_str_mv AT aoifemdoyle thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT helenaweiss thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT kaballamaganja thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT saidikapiga thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT sheenamccormack thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT deborahwatsonjones thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT johnchangalucha thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT richardjhayes thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT davidaross thelongtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT aoifemdoyle longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT helenaweiss longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT kaballamaganja longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT saidikapiga longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT sheenamccormack longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT deborahwatsonjones longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT johnchangalucha longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT richardjhayes longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure
AT davidaross longtermimpactofthememakwavijanaadolescentsexualandreproductivehealthinterventioneffectofdoseandtimesinceinterventionexposure