Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trial
Introduction Currently, the first choice for the clinical treatment of static tremor in Parkinson’s disease (PD) is drug therapy, however side effects are common. In recent years, the effects of physical therapy on PD has become a serious research focus. Studies have indicated that aerobic and resis...
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BMJ Publishing Group
2022-07-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/7/e059625.full |
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| author | Hang Su Xiaoyu Jiang Limin Wang Linlin Zhang Qing Wang Xihua Liu Xiaoming Xi Yuxiao Chen Xinjie Qu Haihao Cao Wenyu Sun Guoming Chen Huifen Liu Jiahui Jiang Hongyan Bi |
| author_facet | Hang Su Xiaoyu Jiang Limin Wang Linlin Zhang Qing Wang Xihua Liu Xiaoming Xi Yuxiao Chen Xinjie Qu Haihao Cao Wenyu Sun Guoming Chen Huifen Liu Jiahui Jiang Hongyan Bi |
| author_sort | Hang Su |
| collection | DOAJ |
| description | Introduction Currently, the first choice for the clinical treatment of static tremor in Parkinson’s disease (PD) is drug therapy, however side effects are common. In recent years, the effects of physical therapy on PD has become a serious research focus. Studies have indicated that aerobic and resistance exercises alleviate PD movement disorders and improve aerobic capacity, but the effects of Qigong on PD static tremor and aerobic capacity remain unknown.Methods and analysis Objective To observe the effects of Zhan Zhuang Qigong on upper limb static tremor and aerobic capacity in patients with PD, we established a rigorous randomised, parallel-controlled, assignment hidden, evaluator-blinded protocol.Methods Seventy-two patients with PD, at the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, were recruited and randomly divided into a control (n=36) and experimental group (n=36). The intervention group received conventional medicine plus Zhan Zhuang Qigong exercises five times a week at 30 min each time, over an 8-week period. The long-term effects of Zhan Zhuang Qigong on PD was investigated after the intervention. Phyphox APP, CRST, CPET, UPDRS(II, III) were used to evaluate tremor, aerobic capacity, and motor function in groups.Discussion We are investigating the effects of Zhan Zhuang Qigong on upper limb static tremor and aerobic capacity in patients with PD. If positive are identified, they will add a new research direction and evidence for the clinical exploration of exercise therapy for PD.Ethics and dissemination This study was approved by the Ethics Committee of Shandong University of Traditional Chinese Medicine (Approval Number: 2021–025-KY). The Committee will be informed of any changes to the trial protocol, such as intervention intensity, outcome indicators and data collection. Study results will be presented as a paper at an international conference or in a journal.Trial registration number ChiCTR2100053529. |
| format | Article |
| id | doaj-art-3b1cf7d3c91a426dae6efe74a7fad301 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-3b1cf7d3c91a426dae6efe74a7fad3012025-01-31T08:05:10ZengBMJ Publishing GroupBMJ Open2044-60552022-07-0112710.1136/bmjopen-2021-059625Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trialHang Su0Xiaoyu Jiang1Limin Wang2Linlin Zhang3Qing Wang4Xihua Liu5Xiaoming Xi6Yuxiao Chen7Xinjie Qu8Haihao Cao9Wenyu Sun10Guoming Chen11Huifen Liu12Jiahui Jiang13Hongyan Bi14Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaDepartment of Rehabilitation Medicine, Beijing Jishuitan Hospital affiliated to Capital Medical University, Beijing, China1 National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China1 Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, ChinaShandong University of Traditional Chinese Medicine, Jinan, chinaShandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, Shandong, China4 Beijing Rehabilitation Hospital Affiliated to Capital Medical University Department of Neurological Rehabilitation, Beijing, Beijing, China2 Universidad de Barcelona, Barcelona, Catalunya, SpainCollege of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaShandong University of Traditional Chinese Medicine, Jinan, chinaDepartment of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, Shandong, ChinaShandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, Shandong, China1 College of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, ChinaThe University of Texas MD Anderson Cancer Center, Houston, TX, USADepartment of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, Shandong, ChinaIntroduction Currently, the first choice for the clinical treatment of static tremor in Parkinson’s disease (PD) is drug therapy, however side effects are common. In recent years, the effects of physical therapy on PD has become a serious research focus. Studies have indicated that aerobic and resistance exercises alleviate PD movement disorders and improve aerobic capacity, but the effects of Qigong on PD static tremor and aerobic capacity remain unknown.Methods and analysis Objective To observe the effects of Zhan Zhuang Qigong on upper limb static tremor and aerobic capacity in patients with PD, we established a rigorous randomised, parallel-controlled, assignment hidden, evaluator-blinded protocol.Methods Seventy-two patients with PD, at the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, were recruited and randomly divided into a control (n=36) and experimental group (n=36). The intervention group received conventional medicine plus Zhan Zhuang Qigong exercises five times a week at 30 min each time, over an 8-week period. The long-term effects of Zhan Zhuang Qigong on PD was investigated after the intervention. Phyphox APP, CRST, CPET, UPDRS(II, III) were used to evaluate tremor, aerobic capacity, and motor function in groups.Discussion We are investigating the effects of Zhan Zhuang Qigong on upper limb static tremor and aerobic capacity in patients with PD. If positive are identified, they will add a new research direction and evidence for the clinical exploration of exercise therapy for PD.Ethics and dissemination This study was approved by the Ethics Committee of Shandong University of Traditional Chinese Medicine (Approval Number: 2021–025-KY). The Committee will be informed of any changes to the trial protocol, such as intervention intensity, outcome indicators and data collection. Study results will be presented as a paper at an international conference or in a journal.Trial registration number ChiCTR2100053529.https://bmjopen.bmj.com/content/12/7/e059625.full |
| spellingShingle | Hang Su Xiaoyu Jiang Limin Wang Linlin Zhang Qing Wang Xihua Liu Xiaoming Xi Yuxiao Chen Xinjie Qu Haihao Cao Wenyu Sun Guoming Chen Huifen Liu Jiahui Jiang Hongyan Bi Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trial BMJ Open |
| title | Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trial |
| title_full | Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trial |
| title_fullStr | Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trial |
| title_full_unstemmed | Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trial |
| title_short | Effect of Zhan Zhuang Qigong on upper limb static tremor and aerobic exercise capacity in patients with mild-to-moderate Parkinson’s disease: study protocol for a randomised controlled trial |
| title_sort | effect of zhan zhuang qigong on upper limb static tremor and aerobic exercise capacity in patients with mild to moderate parkinson s disease study protocol for a randomised controlled trial |
| url | https://bmjopen.bmj.com/content/12/7/e059625.full |
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