Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale
BackgroundMigraine is a common chronic neurological disease， and patent foramen ovale （PFO） has been closely associated with migraine. Current research primarily focuses on the pathological mechanism and the therapeutic effects of interventional closure， with limited attention paid to the impact of...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Sichuan Mental Health
2025-06-01
|
| Series: | Sichuan jingshen weisheng |
| Subjects: | |
| Online Access: | http://www.psychjm.net.cn/scjswszz/ch/reader/view_abstract.aspx?file_no=202503009&flag=1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849709050620542976 |
|---|---|
| author | Hu Yijun Zhang Diwen Wang Libo Liu Bo Ye Hongmei Zhao Xiongfei |
| author_facet | Hu Yijun Zhang Diwen Wang Libo Liu Bo Ye Hongmei Zhao Xiongfei |
| author_sort | Hu Yijun |
| collection | DOAJ |
| description | BackgroundMigraine is a common chronic neurological disease， and patent foramen ovale （PFO） has been closely associated with migraine. Current research primarily focuses on the pathological mechanism and the therapeutic effects of interventional closure， with limited attention paid to the impact of PFO on sleep quality in migraine patients.ObjectiveTo compare the difference in sleep quality between PFO-positive and PFO-negative migraine patients， and to analyzes influencing factors of sleep quality in PFO-positive migraine patients， so as to provide references for clinical interventions to improve sleep quality in PFO-positive migraine patients.MethodsA total of 673 migraine patients who met the diagnostic criteria of migraine in the International Classification of Headache Disorders， third edition （ICHD-3）， and all patients underwent contrast-enhanced transcranial Doppler （c-TCD） and transthoracic echocardiographic right heart contrast echocardiography （cTTE） in the Third Hospital of Mianyang from January 2020 to October 2024. Basic demographic data were collected using a self-designed questionnaire， headache severity was assessed with the Visual Analogue Scale （VAS）， and sleep quality was invaluated using the Pittsburgh Sleep Quality Index （PSQI）. PFO patients was diagnosed through c-TCD combined with c-TTE. Binary logistic regression analysis was employed to examine the influencing factors of sleep quality in PFO-positive migraine patients.ResultsA total of 673 （100.00%） migraine patients were enrolled， including 223 PFO-positive cases （33.14%） and 450 PFO-negative cases（66.86%）. The PFO-positive group showed significantly more severe headache severity （χ2=15.799， P<0.01） and poorer sleep quality （χ2=14.377， P<0.01） compared with PFO-negative group. PFO-positive patients demonstrated significantly higher barrier factor scores of sleep quality， sleep latency， sleep efficiency， sleep disturbance， hypnotic medication use， and daytime dysfunction compared with PFO-negative counterparts （t=3.634， 3.269， 2.785， 3.428， 2.907， 3.637， Bonferroni adjust P<0.05/7=0.007）.By contrast， no significant difference was noted in sleep duration scores between the two groups（t=2.349， Bonferroni adjust P>0.05/7=0.007）.The Binary Logistic regression analysis revealed that age （OR=1.021， 95% CI： 1.001~1.041）， headache severity （OR=6.030， 95% CI： 4.085~8.901）， and PFO grade （OR=1.893，95% CI： 1.288~2.784）were significant influencing factors for sleep quality in migraine patients with PFO.ConclusionMigraine patients with PFO-positive exhibited poorer sleep quality compared wtih PFO-negative patients. Older age， higher headache servity， and more severe PFO grade are identified as risk factors for impaired sleep quality in PFO-positive migraine patients. |
| format | Article |
| id | doaj-art-3b0cc93e2b8140e589b54120426e64a4 |
| institution | DOAJ |
| issn | 1007-3256 |
| language | zho |
| publishDate | 2025-06-01 |
| publisher | Editorial Office of Sichuan Mental Health |
| record_format | Article |
| series | Sichuan jingshen weisheng |
| spelling | doaj-art-3b0cc93e2b8140e589b54120426e64a42025-08-20T03:15:27ZzhoEditorial Office of Sichuan Mental HealthSichuan jingshen weisheng1007-32562025-06-0138324124610.11886/scjsws202501020031007-3256（2025）03-0241-06Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovaleHu Yijun0Zhang Diwen1Wang Libo2Liu Bo3Ye Hongmei4Zhao Xiongfei5Sichuan Mental Health Center·The Third Hospital of Mianyang， Mianyang 621000， ChinaSichuan Mental Health Center·The Third Hospital of Mianyang， Mianyang 621000， ChinaSichuan Mental Health Center·The Third Hospital of Mianyang， Mianyang 621000， ChinaShenzhen Longhua District Central Hospital， Shenzhen 518110， ChinaSichuan Mental Health Center·The Third Hospital of Mianyang， Mianyang 621000， ChinaSichuan Mental Health Center·The Third Hospital of Mianyang， Mianyang 621000， ChinaBackgroundMigraine is a common chronic neurological disease， and patent foramen ovale （PFO） has been closely associated with migraine. Current research primarily focuses on the pathological mechanism and the therapeutic effects of interventional closure， with limited attention paid to the impact of PFO on sleep quality in migraine patients.ObjectiveTo compare the difference in sleep quality between PFO-positive and PFO-negative migraine patients， and to analyzes influencing factors of sleep quality in PFO-positive migraine patients， so as to provide references for clinical interventions to improve sleep quality in PFO-positive migraine patients.MethodsA total of 673 migraine patients who met the diagnostic criteria of migraine in the International Classification of Headache Disorders， third edition （ICHD-3）， and all patients underwent contrast-enhanced transcranial Doppler （c-TCD） and transthoracic echocardiographic right heart contrast echocardiography （cTTE） in the Third Hospital of Mianyang from January 2020 to October 2024. Basic demographic data were collected using a self-designed questionnaire， headache severity was assessed with the Visual Analogue Scale （VAS）， and sleep quality was invaluated using the Pittsburgh Sleep Quality Index （PSQI）. PFO patients was diagnosed through c-TCD combined with c-TTE. Binary logistic regression analysis was employed to examine the influencing factors of sleep quality in PFO-positive migraine patients.ResultsA total of 673 （100.00%） migraine patients were enrolled， including 223 PFO-positive cases （33.14%） and 450 PFO-negative cases（66.86%）. The PFO-positive group showed significantly more severe headache severity （χ2=15.799， P<0.01） and poorer sleep quality （χ2=14.377， P<0.01） compared with PFO-negative group. PFO-positive patients demonstrated significantly higher barrier factor scores of sleep quality， sleep latency， sleep efficiency， sleep disturbance， hypnotic medication use， and daytime dysfunction compared with PFO-negative counterparts （t=3.634， 3.269， 2.785， 3.428， 2.907， 3.637， Bonferroni adjust P<0.05/7=0.007）.By contrast， no significant difference was noted in sleep duration scores between the two groups（t=2.349， Bonferroni adjust P>0.05/7=0.007）.The Binary Logistic regression analysis revealed that age （OR=1.021， 95% CI： 1.001~1.041）， headache severity （OR=6.030， 95% CI： 4.085~8.901）， and PFO grade （OR=1.893，95% CI： 1.288~2.784）were significant influencing factors for sleep quality in migraine patients with PFO.ConclusionMigraine patients with PFO-positive exhibited poorer sleep quality compared wtih PFO-negative patients. Older age， higher headache servity， and more severe PFO grade are identified as risk factors for impaired sleep quality in PFO-positive migraine patients.http://www.psychjm.net.cn/scjswszz/ch/reader/view_abstract.aspx?file_no=202503009&flag=1migrainepatent foramen ovalesleep quality |
| spellingShingle | Hu Yijun Zhang Diwen Wang Libo Liu Bo Ye Hongmei Zhao Xiongfei Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale Sichuan jingshen weisheng migraine patent foramen ovale sleep quality |
| title | Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale |
| title_full | Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale |
| title_fullStr | Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale |
| title_full_unstemmed | Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale |
| title_short | Analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale |
| title_sort | analysis of sleep quality and influencing factors in migraine patients with patent foramen ovale |
| topic | migraine patent foramen ovale sleep quality |
| url | http://www.psychjm.net.cn/scjswszz/ch/reader/view_abstract.aspx?file_no=202503009&flag=1 |
| work_keys_str_mv | AT huyijun analysisofsleepqualityandinfluencingfactorsinmigrainepatientswithpatentforamenovale AT zhangdiwen analysisofsleepqualityandinfluencingfactorsinmigrainepatientswithpatentforamenovale AT wanglibo analysisofsleepqualityandinfluencingfactorsinmigrainepatientswithpatentforamenovale AT liubo analysisofsleepqualityandinfluencingfactorsinmigrainepatientswithpatentforamenovale AT yehongmei analysisofsleepqualityandinfluencingfactorsinmigrainepatientswithpatentforamenovale AT zhaoxiongfei analysisofsleepqualityandinfluencingfactorsinmigrainepatientswithpatentforamenovale |