3-Methyl-2-(5-((trimethylsilyl)ethynyl)pyridin-2-yl)butan-2-ol

The reactions of dialkylzinc reagents with ketones are scarcely studied. In this paper, we describe a previously unknown direct alkylation of substituted 2-acetylpyridine with diisopropyl zinc, which gave a corresponding novel alcohol with 82% yield.

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Bibliographic Details
Main Authors: Oleg A. Mikhailov, Almira R. Kurbangalieva, Ilya D. Gridnev
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2024/4/M1925
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Description
Summary:The reactions of dialkylzinc reagents with ketones are scarcely studied. In this paper, we describe a previously unknown direct alkylation of substituted 2-acetylpyridine with diisopropyl zinc, which gave a corresponding novel alcohol with 82% yield.
ISSN:1422-8599