Assessing infection related to short-term central venous catheters in the perioperative setting
Abstract Central venous catheter (CVC) cannulation can be accompanied by serious complications. The appearance of catheter-related infections is associated with high morbimortality. The aim of this study is to evaluate the incidences of colonization and central line-associated bloodstream infections...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-85836-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841544810041704448 |
|---|---|
| author | Ángel Becerra-Bolaños Yurena Domínguez-Díaz Héctor Trujillo-Morales Sergio Cabrera-Doreste Oto Padrón-Ruiz Lucía Valencia-Sola Nazario Ojeda-Betancor Aurelio Rodríguez-Pérez |
| author_facet | Ángel Becerra-Bolaños Yurena Domínguez-Díaz Héctor Trujillo-Morales Sergio Cabrera-Doreste Oto Padrón-Ruiz Lucía Valencia-Sola Nazario Ojeda-Betancor Aurelio Rodríguez-Pérez |
| author_sort | Ángel Becerra-Bolaños |
| collection | DOAJ |
| description | Abstract Central venous catheter (CVC) cannulation can be accompanied by serious complications. The appearance of catheter-related infections is associated with high morbimortality. The aim of this study is to evaluate the incidences of colonization and central line-associated bloodstream infections (CLABSI) in short-term CVCs in the elective surgery setting, as well as to analyze the related risk factors. Prospective observational study including patients undergoing elective surgery with a CVC inserted perioperatively. Patients with current infection, taking preoperative antibiotics, those planning to have CVC for longer than 14 days, those under 18 years old, and those refusing to participate were excluded. Patients without cultures at the moment of CVC retrieval were not included. 200 patients were included, with a mean catheter duration of 6.8 ± 3.1 days, and a total duration of 1,358 days. Incidence of colonized catheters was 6% (8.84/1000 catheter-days), and 3.5% had CLABSI (5.15/1000 catheter-days). Catheter duration was longer in patients whose CVCs had been removed due to suspected infection (p < 0.0001). The risk factors for catheter colonization were a history of oncological disease (p = 0.022), ischemic heart disease (p = 0.019), as well as jugular venous catheterization (p = 0.019). No relationship was detected between colonization and operator experience (p = 0.050), ultrasound-guided cannulation (p = 0.565), or number of attempts (p = 0.379). The risk factors for CLABSI were: age over 60 years (p = 0.041) and oncological disease (p = 0.021). CLABSI was neither related to operator experience (p = 0.178), ultrasound-guided cannulation (p = 0.373), or number of attempts (p = 0.379). Although CVCs were in place for a short time and in a controlled setting, we observed high incidences of colonization and CLABSI. The risk of catheter colonization depends on other factors rather than catheter duration. |
| format | Article |
| id | doaj-art-3b092339063a435e829ac4437310e9ca |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-3b092339063a435e829ac4437310e9ca2025-01-12T12:14:46ZengNature PortfolioScientific Reports2045-23222025-01-0115111110.1038/s41598-025-85836-zAssessing infection related to short-term central venous catheters in the perioperative settingÁngel Becerra-Bolaños0Yurena Domínguez-Díaz1Héctor Trujillo-Morales2Sergio Cabrera-Doreste3Oto Padrón-Ruiz4Lucía Valencia-Sola5Nazario Ojeda-Betancor6Aurelio Rodríguez-Pérez7Department of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínDepartment of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínDepartment of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínDepartment of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínDepartment of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínDepartment of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínDepartment of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínDepartment of Anesthesiology, Intensive Care and Pain Medicine, Hospital Universitario de Gran Canaria Doctor NegrínAbstract Central venous catheter (CVC) cannulation can be accompanied by serious complications. The appearance of catheter-related infections is associated with high morbimortality. The aim of this study is to evaluate the incidences of colonization and central line-associated bloodstream infections (CLABSI) in short-term CVCs in the elective surgery setting, as well as to analyze the related risk factors. Prospective observational study including patients undergoing elective surgery with a CVC inserted perioperatively. Patients with current infection, taking preoperative antibiotics, those planning to have CVC for longer than 14 days, those under 18 years old, and those refusing to participate were excluded. Patients without cultures at the moment of CVC retrieval were not included. 200 patients were included, with a mean catheter duration of 6.8 ± 3.1 days, and a total duration of 1,358 days. Incidence of colonized catheters was 6% (8.84/1000 catheter-days), and 3.5% had CLABSI (5.15/1000 catheter-days). Catheter duration was longer in patients whose CVCs had been removed due to suspected infection (p < 0.0001). The risk factors for catheter colonization were a history of oncological disease (p = 0.022), ischemic heart disease (p = 0.019), as well as jugular venous catheterization (p = 0.019). No relationship was detected between colonization and operator experience (p = 0.050), ultrasound-guided cannulation (p = 0.565), or number of attempts (p = 0.379). The risk factors for CLABSI were: age over 60 years (p = 0.041) and oncological disease (p = 0.021). CLABSI was neither related to operator experience (p = 0.178), ultrasound-guided cannulation (p = 0.373), or number of attempts (p = 0.379). Although CVCs were in place for a short time and in a controlled setting, we observed high incidences of colonization and CLABSI. The risk of catheter colonization depends on other factors rather than catheter duration.https://doi.org/10.1038/s41598-025-85836-zCentral venous catheterizationPerioperative instrumentationCatheter related infectionsBacteremiaPerioperative period/TherapyComplications |
| spellingShingle | Ángel Becerra-Bolaños Yurena Domínguez-Díaz Héctor Trujillo-Morales Sergio Cabrera-Doreste Oto Padrón-Ruiz Lucía Valencia-Sola Nazario Ojeda-Betancor Aurelio Rodríguez-Pérez Assessing infection related to short-term central venous catheters in the perioperative setting Scientific Reports Central venous catheterization Perioperative instrumentation Catheter related infections Bacteremia Perioperative period/Therapy Complications |
| title | Assessing infection related to short-term central venous catheters in the perioperative setting |
| title_full | Assessing infection related to short-term central venous catheters in the perioperative setting |
| title_fullStr | Assessing infection related to short-term central venous catheters in the perioperative setting |
| title_full_unstemmed | Assessing infection related to short-term central venous catheters in the perioperative setting |
| title_short | Assessing infection related to short-term central venous catheters in the perioperative setting |
| title_sort | assessing infection related to short term central venous catheters in the perioperative setting |
| topic | Central venous catheterization Perioperative instrumentation Catheter related infections Bacteremia Perioperative period/Therapy Complications |
| url | https://doi.org/10.1038/s41598-025-85836-z |
| work_keys_str_mv | AT angelbecerrabolanos assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting AT yurenadominguezdiaz assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting AT hectortrujillomorales assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting AT sergiocabreradoreste assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting AT otopadronruiz assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting AT luciavalenciasola assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting AT nazarioojedabetancor assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting AT aureliorodriguezperez assessinginfectionrelatedtoshorttermcentralvenouscathetersintheperioperativesetting |