Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats
Amnia melanocarpa fruits are one of the richest natural sources of phenolic substances, among them flavonoids, mainly from the subclass of anthocyanins. Flavonoids, which are constituents of Amnia melanocarpa fruit juice, have been found to localize in various brain regions that are important for me...
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| Format: | Article |
| Language: | English |
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Medical University - Pleven
2013-07-01
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| Series: | Journal of Biomedical & Clinical Research |
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| Online Access: | https://jbcr.arphahub.com/article/34291/download/pdf/ |
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| author | Stefka Valcheva-Kuzmanova Miroslav Eftimov Iren Beleheva Roman Tashev Stiliana Beleheva |
| author_facet | Stefka Valcheva-Kuzmanova Miroslav Eftimov Iren Beleheva Roman Tashev Stiliana Beleheva |
| author_sort | Stefka Valcheva-Kuzmanova |
| collection | DOAJ |
| description | Amnia melanocarpa fruits are one of the richest natural sources of phenolic substances, among them flavonoids, mainly from the subclass of anthocyanins. Flavonoids, which are constituents of Amnia melanocarpa fruit juice, have been found to localize in various brain regions that are important for memory. The aim of the present study was to investigate the learning and memory effects of Amnia melanocarpa fruit juice (AMFJ) in young/healthy male Wistarrats. AMFJ was applied orally for 21 and 30 days at a dose of 10 ml/kg b.w., and comparisons were made with saline-treated (10 ml/kg b.w.) controls. Learning and memory functions were evaluated, using the two-way active avoidance task (shuttle box). Administered for the two treatment periods, the juice significantly increased the number of avoidances on training days 1 and 2, as well as at the retention test (24 h after the 2nd training session). These effects were more pronounced in rats treated with AMFJ for 30 days. The learning and memory effects of AMFJ are probably due to its polyphenolic constituents. The findings from the present study suggest that AMFJ applied subchronically improved learning and memory in young/healthy rats. |
| format | Article |
| id | doaj-art-3afc548433d7470d95fa9b1895cc0d11 |
| institution | Kabale University |
| issn | 1313-9053 |
| language | English |
| publishDate | 2013-07-01 |
| publisher | Medical University - Pleven |
| record_format | Article |
| series | Journal of Biomedical & Clinical Research |
| spelling | doaj-art-3afc548433d7470d95fa9b1895cc0d112025-08-20T03:35:40ZengMedical University - PlevenJournal of Biomedical & Clinical Research1313-90532013-07-0161182310.1515/jbcr-2015-009834291Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in RatsStefka Valcheva-KuzmanovaMiroslav EftimovIren BelehevaRoman TashevStiliana BelehevaAmnia melanocarpa fruits are one of the richest natural sources of phenolic substances, among them flavonoids, mainly from the subclass of anthocyanins. Flavonoids, which are constituents of Amnia melanocarpa fruit juice, have been found to localize in various brain regions that are important for memory. The aim of the present study was to investigate the learning and memory effects of Amnia melanocarpa fruit juice (AMFJ) in young/healthy male Wistarrats. AMFJ was applied orally for 21 and 30 days at a dose of 10 ml/kg b.w., and comparisons were made with saline-treated (10 ml/kg b.w.) controls. Learning and memory functions were evaluated, using the two-way active avoidance task (shuttle box). Administered for the two treatment periods, the juice significantly increased the number of avoidances on training days 1 and 2, as well as at the retention test (24 h after the 2nd training session). These effects were more pronounced in rats treated with AMFJ for 30 days. The learning and memory effects of AMFJ are probably due to its polyphenolic constituents. The findings from the present study suggest that AMFJ applied subchronically improved learning and memory in young/healthy rats.https://jbcr.arphahub.com/article/34291/download/pdf/Aronia melanocarpalearningmemoryactive avoid |
| spellingShingle | Stefka Valcheva-Kuzmanova Miroslav Eftimov Iren Beleheva Roman Tashev Stiliana Beleheva Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats Journal of Biomedical & Clinical Research Aronia melanocarpa learning memory active avoid |
| title | Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats |
| title_full | Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats |
| title_fullStr | Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats |
| title_full_unstemmed | Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats |
| title_short | Effect of Aronia Melanocarpa Fruit Juice on Fearning and Memory in the Two-Way Active Avoidance Task in Rats |
| title_sort | effect of aronia melanocarpa fruit juice on fearning and memory in the two way active avoidance task in rats |
| topic | Aronia melanocarpa learning memory active avoid |
| url | https://jbcr.arphahub.com/article/34291/download/pdf/ |
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