Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT Studies

Conclusions: Gels supplemented with nanoparticles show potential antimicrobial efficacy in vitro, but the evidence from clinical trials is inconsistent. High heterogeneity and potential publication bias indicate the need for more standardized clinical research to accurately assess the effectiveness...

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Main Authors: Pedro Rosales García, Eva Concepción Aguirre López, José Eduardo Pérez Romano, Jorge Humberto Luna Domínguez, Nuria Patiño Marín, Alan Martínez Zumarán, Idania De Alba Montero, Marco Felipe Salas Orozco
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Journal of Nanotechnology
Online Access:http://dx.doi.org/10.1155/jnt/8412675
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author Pedro Rosales García
Eva Concepción Aguirre López
José Eduardo Pérez Romano
Jorge Humberto Luna Domínguez
Nuria Patiño Marín
Alan Martínez Zumarán
Idania De Alba Montero
Marco Felipe Salas Orozco
author_facet Pedro Rosales García
Eva Concepción Aguirre López
José Eduardo Pérez Romano
Jorge Humberto Luna Domínguez
Nuria Patiño Marín
Alan Martínez Zumarán
Idania De Alba Montero
Marco Felipe Salas Orozco
author_sort Pedro Rosales García
collection DOAJ
description Conclusions: Gels supplemented with nanoparticles show potential antimicrobial efficacy in vitro, but the evidence from clinical trials is inconsistent. High heterogeneity and potential publication bias indicate the need for more standardized clinical research to accurately assess the effectiveness of nanoparticle-supplemented gels in endodontic treatment.
format Article
id doaj-art-3af3fd04cafc4f65b9fa5cd2b4c29d68
institution Kabale University
issn 1687-9511
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Journal of Nanotechnology
spelling doaj-art-3af3fd04cafc4f65b9fa5cd2b4c29d682025-08-20T03:41:50ZengWileyJournal of Nanotechnology1687-95112025-01-01202510.1155/jnt/8412675Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT StudiesPedro Rosales García0Eva Concepción Aguirre López1José Eduardo Pérez Romano2Jorge Humberto Luna Domínguez3Nuria Patiño Marín4Alan Martínez Zumarán5Idania De Alba Montero6Marco Felipe Salas Orozco7Facultad de Estomatología del Complejo Regional Nororiental de la Benemérita Universidad Autónoma deFaculty of StomatologyFacultad de Estomatología del Complejo Regional Nororiental de la Benemérita Universidad Autónoma deResearch CenterFaculty of StomatologyFaculty of StomatologyFaculty of SciencesFaculty of StomatologyConclusions: Gels supplemented with nanoparticles show potential antimicrobial efficacy in vitro, but the evidence from clinical trials is inconsistent. High heterogeneity and potential publication bias indicate the need for more standardized clinical research to accurately assess the effectiveness of nanoparticle-supplemented gels in endodontic treatment.http://dx.doi.org/10.1155/jnt/8412675
spellingShingle Pedro Rosales García
Eva Concepción Aguirre López
José Eduardo Pérez Romano
Jorge Humberto Luna Domínguez
Nuria Patiño Marín
Alan Martínez Zumarán
Idania De Alba Montero
Marco Felipe Salas Orozco
Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT Studies
Journal of Nanotechnology
title Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT Studies
title_full Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT Studies
title_fullStr Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT Studies
title_full_unstemmed Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT Studies
title_short Antimicrobial Activity of Gels Supplemented With Nanoparticles as Intracanal Medication in Endodontics: A Systematic Review and Meta-Analysis of In Vitro, In Vivo, and RCT Studies
title_sort antimicrobial activity of gels supplemented with nanoparticles as intracanal medication in endodontics a systematic review and meta analysis of in vitro in vivo and rct studies
url http://dx.doi.org/10.1155/jnt/8412675
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