Review on Helicobacter pylori associated Diseases

One of the most common and enduring bacterial infections globally, Helicobacter pylori (H. pylori) infects almost half of the world’s population. The bacterium is described as a spiral microaerophilic gram-negative bacterium; it is commonly found in the stomach and can cause several categories of ga...

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Main Authors: SHahrazad H. Muhi, Farah Badri Abed, Nada H. Bedair, Saba R. Jaafar, Sahar M. Ibrahim, Dunya Abdullah Mohammed, Omar A. Mahmoud, Ruaa H. Ali, Mohammed Ayad Hameed, Luma Mahmood Edan
Format: Article
Language:English
Published: College of Medicine, Al-Nahrain University 2024-09-01
Series:Baghdad Journal of Biochemistry and Applied Biological Sciences
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Online Access:https://www.bjbabs.org/index.php/bjbabs/article/view/307
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author SHahrazad H. Muhi
Farah Badri Abed
Nada H. Bedair
Saba R. Jaafar
Sahar M. Ibrahim
Dunya Abdullah Mohammed
Omar A. Mahmoud
Ruaa H. Ali
Mohammed Ayad Hameed
Luma Mahmood Edan
author_facet SHahrazad H. Muhi
Farah Badri Abed
Nada H. Bedair
Saba R. Jaafar
Sahar M. Ibrahim
Dunya Abdullah Mohammed
Omar A. Mahmoud
Ruaa H. Ali
Mohammed Ayad Hameed
Luma Mahmood Edan
author_sort SHahrazad H. Muhi
collection DOAJ
description One of the most common and enduring bacterial infections globally, Helicobacter pylori (H. pylori) infects almost half of the world’s population. The bacterium is described as a spiral microaerophilic gram-negative bacterium; it is commonly found in the stomach and can cause several categories of gastrointestinal conditions, such as gastritis, peptic ulcers, and in some circumstances, stomach cancer. There is also a growing knowledge that chronic H. pylori infection may be associated with an increased danger of extra-gastric disease that includes host iron deficiency anemia, and cardiovascular, autoimmune, metabolic, neurological, and dermatological diseases. In this article, we examined the virulence factors of H. pylori and its correlation to gastrointestinal diseases, as well as the bacterium’s potential involvement in extra-gastric diseases such as iron and vitamin B12 deficiency, in addition to neurological, cardiovascular, inflammatory bowel, and diabetes mellitus disorders.
format Article
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institution DOAJ
issn 2706-9915
language English
publishDate 2024-09-01
publisher College of Medicine, Al-Nahrain University
record_format Article
series Baghdad Journal of Biochemistry and Applied Biological Sciences
spelling doaj-art-3af17aa9edce4836a8f2d8bec6386d882025-08-20T02:57:29ZengCollege of Medicine, Al-Nahrain UniversityBaghdad Journal of Biochemistry and Applied Biological Sciences2706-99152024-09-015313414310.47419/bjbabs.v5i3.307Review on Helicobacter pylori associated DiseasesSHahrazad H. Muhi0https://orcid.org/0009-0004-1148-3762Farah Badri Abed1https://orcid.org/0000-0003-1356-2304Nada H. Bedair2https://orcid.org/0000-0003-1852-0154Saba R. Jaafar3https://orcid.org/0009-0006-5576-6902Sahar M. Ibrahim4https://orcid.org/0009-0005-6638-9498Dunya Abdullah Mohammed5https://orcid.org/0009-0009-0541-8194Omar A. Mahmoud6https://orcid.org/0009-0005-6884-9398Ruaa H. Ali7https://orcid.org/0009-0003-1501-9871Mohammed Ayad Hameed8https://orcid.org/0009-0000-8621-3696Luma Mahmood Edan9https://orcid.org/0000-0001-5781-8768Higher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqHigher Institute of Forensic Sciences, Al-Nahrain University, Baghdad, IraqOne of the most common and enduring bacterial infections globally, Helicobacter pylori (H. pylori) infects almost half of the world’s population. The bacterium is described as a spiral microaerophilic gram-negative bacterium; it is commonly found in the stomach and can cause several categories of gastrointestinal conditions, such as gastritis, peptic ulcers, and in some circumstances, stomach cancer. There is also a growing knowledge that chronic H. pylori infection may be associated with an increased danger of extra-gastric disease that includes host iron deficiency anemia, and cardiovascular, autoimmune, metabolic, neurological, and dermatological diseases. In this article, we examined the virulence factors of H. pylori and its correlation to gastrointestinal diseases, as well as the bacterium’s potential involvement in extra-gastric diseases such as iron and vitamin B12 deficiency, in addition to neurological, cardiovascular, inflammatory bowel, and diabetes mellitus disorders.https://www.bjbabs.org/index.php/bjbabs/article/view/307h. pylorigastric diseaseextra gastric manifestations
spellingShingle SHahrazad H. Muhi
Farah Badri Abed
Nada H. Bedair
Saba R. Jaafar
Sahar M. Ibrahim
Dunya Abdullah Mohammed
Omar A. Mahmoud
Ruaa H. Ali
Mohammed Ayad Hameed
Luma Mahmood Edan
Review on Helicobacter pylori associated Diseases
Baghdad Journal of Biochemistry and Applied Biological Sciences
h. pylori
gastric disease
extra gastric manifestations
title Review on Helicobacter pylori associated Diseases
title_full Review on Helicobacter pylori associated Diseases
title_fullStr Review on Helicobacter pylori associated Diseases
title_full_unstemmed Review on Helicobacter pylori associated Diseases
title_short Review on Helicobacter pylori associated Diseases
title_sort review on helicobacter pylori associated diseases
topic h. pylori
gastric disease
extra gastric manifestations
url https://www.bjbabs.org/index.php/bjbabs/article/view/307
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AT farahbadriabed reviewonhelicobacterpyloriassociateddiseases
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AT sabarjaafar reviewonhelicobacterpyloriassociateddiseases
AT saharmibrahim reviewonhelicobacterpyloriassociateddiseases
AT dunyaabdullahmohammed reviewonhelicobacterpyloriassociateddiseases
AT omaramahmoud reviewonhelicobacterpyloriassociateddiseases
AT ruaahali reviewonhelicobacterpyloriassociateddiseases
AT mohammedayadhameed reviewonhelicobacterpyloriassociateddiseases
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