Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021
Background & Aims: The Ministry of Health and Treatment implemented vaccination as one of the primary strategies to control the coronavirus disease 2019 (COVID-19) pandemic. Given their critical role in treatment and disease control, healthcare workers were prioritized for vaccination. This stu...
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| Language: | English |
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Urmia University of Medical Sciences
2025-02-01
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| Series: | Health Science Monitor |
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| Online Access: | http://hsm.umsu.ac.ir/article-1-191-en.pdf |
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| author | Maryam Taavon Vahid Tanhaei Marand Sadegh Feizollahzadeh |
| author_facet | Maryam Taavon Vahid Tanhaei Marand Sadegh Feizollahzadeh |
| author_sort | Maryam Taavon |
| collection | DOAJ |
| description | Background & Aims: The Ministry of Health and Treatment implemented vaccination as one of the primary strategies to control the coronavirus disease 2019 (COVID-19) pandemic. Given their critical role in treatment and disease control, healthcare workers were prioritized for vaccination. This study aims to assess the vaccination status and level of immunity against COVID-19 among healthcare workers at Shahid Motahari Hospital in Urmia, Iran, in 2021.
Materials & Methods: A cross-sectional study was conducted with 150 volunteer healthcare workers at Shahid Motahari Hospital. Venous blood samples were collected to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies using the ELISA method. Data analysis was performed using version 16 of SPSS software.
Results: The participants had a mean age of 37.5 years, with 47.3% being male. A significant 98% of the participants were vaccinated against COVID-19. The predominant vaccines administered were Sputnik V (72%), AstraZeneca (54%), and Sinopharm (27%). The mean level of SARS-CoV-2 neutralizing antibodies was significantly higher in vaccinated individuals compared to unvaccinated individuals (p = 0.001). There was no significant difference in antibody levels between male and female participants (p = 0.67). A positive correlation was observed between the number of vaccine doses received and the level of neutralizing antibodies (R = 0.207).
Conclusion: Vaccination with the mentioned vaccines, whether administered singly or in combination, effectively increased serum antibody levels, providing sufficient protection against COVID-19 for healthcare workers. To maintain immunity levels among healthcare workers and protect against emerging strains of the virus, it is essential to administer booster doses. |
| format | Article |
| id | doaj-art-3af026c9287d42e49e786dbb42ace34e |
| institution | OA Journals |
| issn | 2980-8723 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Urmia University of Medical Sciences |
| record_format | Article |
| series | Health Science Monitor |
| spelling | doaj-art-3af026c9287d42e49e786dbb42ace34e2025-08-20T02:11:17ZengUrmia University of Medical SciencesHealth Science Monitor2980-87232025-02-0141714Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021Maryam Taavon0Vahid Tanhaei Marand1Sadegh Feizollahzadeh2 MSc student in Microbiology, Faculty of Basic Sciences, Urmia Branch, Islamic Azad University, Urmia, Iran Assistant Professor, Department of Biology, Urmia Branch, Islamic Azad University, Urmia, Iran Assistant Professor of Immunology, Department of Immunology and Genetics, Faculty of Medicine, Urmia University of Medical Sciences, Urmia, Iran Background & Aims: The Ministry of Health and Treatment implemented vaccination as one of the primary strategies to control the coronavirus disease 2019 (COVID-19) pandemic. Given their critical role in treatment and disease control, healthcare workers were prioritized for vaccination. This study aims to assess the vaccination status and level of immunity against COVID-19 among healthcare workers at Shahid Motahari Hospital in Urmia, Iran, in 2021. Materials & Methods: A cross-sectional study was conducted with 150 volunteer healthcare workers at Shahid Motahari Hospital. Venous blood samples were collected to measure severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies using the ELISA method. Data analysis was performed using version 16 of SPSS software. Results: The participants had a mean age of 37.5 years, with 47.3% being male. A significant 98% of the participants were vaccinated against COVID-19. The predominant vaccines administered were Sputnik V (72%), AstraZeneca (54%), and Sinopharm (27%). The mean level of SARS-CoV-2 neutralizing antibodies was significantly higher in vaccinated individuals compared to unvaccinated individuals (p = 0.001). There was no significant difference in antibody levels between male and female participants (p = 0.67). A positive correlation was observed between the number of vaccine doses received and the level of neutralizing antibodies (R = 0.207). Conclusion: Vaccination with the mentioned vaccines, whether administered singly or in combination, effectively increased serum antibody levels, providing sufficient protection against COVID-19 for healthcare workers. To maintain immunity levels among healthcare workers and protect against emerging strains of the virus, it is essential to administer booster doses.http://hsm.umsu.ac.ir/article-1-191-en.pdfcovid-19immunity leveliranhealthcare workersvaccination |
| spellingShingle | Maryam Taavon Vahid Tanhaei Marand Sadegh Feizollahzadeh Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021 Health Science Monitor covid-19 immunity level iran healthcare workers vaccination |
| title | Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021 |
| title_full | Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021 |
| title_fullStr | Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021 |
| title_full_unstemmed | Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021 |
| title_short | Evaluation of COVID-19 vaccination status and immune response among staff at Shahid Motahari Hospital, Urmia, 2021 |
| title_sort | evaluation of covid 19 vaccination status and immune response among staff at shahid motahari hospital urmia 2021 |
| topic | covid-19 immunity level iran healthcare workers vaccination |
| url | http://hsm.umsu.ac.ir/article-1-191-en.pdf |
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