14-3-3 Proteins in Glutamatergic Synapses
The 14-3-3 proteins are a family of proteins that are highly expressed in the brain and particularly enriched at synapses. Evidence accumulated in the last two decades has implicated 14-3-3 proteins as an important regulator of synaptic transmission and plasticity. Here, we will review previous and...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Neural Plasticity |
| Online Access: | http://dx.doi.org/10.1155/2018/8407609 |
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| _version_ | 1832549088242958336 |
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| author | Jiajing Zhang Yi Zhou |
| author_facet | Jiajing Zhang Yi Zhou |
| author_sort | Jiajing Zhang |
| collection | DOAJ |
| description | The 14-3-3 proteins are a family of proteins that are highly expressed in the brain and particularly enriched at synapses. Evidence accumulated in the last two decades has implicated 14-3-3 proteins as an important regulator of synaptic transmission and plasticity. Here, we will review previous and more recent research that has helped us understand the roles of 14-3-3 proteins at glutamatergic synapses. A key challenge for the future is to delineate the 14-3-3-dependent molecular pathways involved in regulating synaptic functions. |
| format | Article |
| id | doaj-art-3ae9fec508ad4397be4c5fa40652e883 |
| institution | Kabale University |
| issn | 2090-5904 1687-5443 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neural Plasticity |
| spelling | doaj-art-3ae9fec508ad4397be4c5fa40652e8832025-02-03T06:12:17ZengWileyNeural Plasticity2090-59041687-54432018-01-01201810.1155/2018/8407609840760914-3-3 Proteins in Glutamatergic SynapsesJiajing Zhang0Yi Zhou1Department of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306, USADepartment of Biomedical Sciences, Florida State University College of Medicine, Tallahassee, FL 32306, USAThe 14-3-3 proteins are a family of proteins that are highly expressed in the brain and particularly enriched at synapses. Evidence accumulated in the last two decades has implicated 14-3-3 proteins as an important regulator of synaptic transmission and plasticity. Here, we will review previous and more recent research that has helped us understand the roles of 14-3-3 proteins at glutamatergic synapses. A key challenge for the future is to delineate the 14-3-3-dependent molecular pathways involved in regulating synaptic functions.http://dx.doi.org/10.1155/2018/8407609 |
| spellingShingle | Jiajing Zhang Yi Zhou 14-3-3 Proteins in Glutamatergic Synapses Neural Plasticity |
| title | 14-3-3 Proteins in Glutamatergic Synapses |
| title_full | 14-3-3 Proteins in Glutamatergic Synapses |
| title_fullStr | 14-3-3 Proteins in Glutamatergic Synapses |
| title_full_unstemmed | 14-3-3 Proteins in Glutamatergic Synapses |
| title_short | 14-3-3 Proteins in Glutamatergic Synapses |
| title_sort | 14 3 3 proteins in glutamatergic synapses |
| url | http://dx.doi.org/10.1155/2018/8407609 |
| work_keys_str_mv | AT jiajingzhang 1433proteinsinglutamatergicsynapses AT yizhou 1433proteinsinglutamatergicsynapses |