Bacteria‐Mediated Tumor‐Targeting Delivery of Multienzyme‐Mimicking Covalent Organic Frameworks Promoting Pyroptosis for Combinatorial Sono‐Catalytic Immunotherapy

Bacteria‐Mediated Tumor‐Targeting Delivery of Multienzyme‐Mimicking Covalent Organic Frameworks Promoting Pyroptosis for Combinatorial Sono‐Catalytic Immunotherapy

Abstract Pyroptosis, an inflammatory cell death, has attracted great attention for potentiating a strong immune response against tumor cells. However, developing powerful pyroptosis inducers and then activating specific pyroptosis still remains challenging. Herein, a PEG‐CuP‐COF@∆St nanosystem is ra...

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Main Authors: Yunyun Liu, Lihua Xiang, Yitong Li, Shen Zhang, Ying Zhang, Hui Shi, Hui Liu, Dou Du, Bangguo Zhou, Beibei Ye, Shaoyue Li, Haohao Yin, Huixiong Xu, Yifeng Zhang
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
immunotherapy
multienzyme mimicking
pyroptosis
tumor‐targeting delivery
ultrasound
Online Access:https://doi.org/10.1002/advs.202407133
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