Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux

Quercetin alleviates LPS/iE-DAP-induced liver injury by suppressing ferroptosis via regulating ferritinophagy and intracellular iron efflux

Ruminal dysbiosis-induced liver injury is prevalent in dairy cows, yet its underlying mechanisms remain incompletely understood. Ferroptosis, a newly identified form of programmed cell death distinct from apoptosis and necrosis, has been implicated in various liver diseases by emerging studies. In t...

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Bibliographic Details
Main Authors: Hongzhu Zhang, Huimin Shi, Xuerui Li, Shendong Zhou, Xiaokun Song, Nana Ma, Meijuan Meng, Guangjun Chang, Xiangzhen Shen
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Redox Biology
Subjects:
Ferroptosis
Ferritinophagy
Iron metabolism
Ruminal dysbiosis
Liver injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231725000709
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