A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing

The two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as prom...

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Main Authors: Shih-Feng Chou, Simi Gunaseelan, Mhd Hussam Hijazi Kiellani, Venkata Vamsi Krishna Thottempudi, Pierre Neuenschwander, Huarong Nie
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Nanotechnology
Online Access:http://dx.doi.org/10.1155/2017/6341710
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author Shih-Feng Chou
Simi Gunaseelan
Mhd Hussam Hijazi Kiellani
Venkata Vamsi Krishna Thottempudi
Pierre Neuenschwander
Huarong Nie
author_facet Shih-Feng Chou
Simi Gunaseelan
Mhd Hussam Hijazi Kiellani
Venkata Vamsi Krishna Thottempudi
Pierre Neuenschwander
Huarong Nie
author_sort Shih-Feng Chou
collection DOAJ
description The two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as promote tissue regeneration. In this short review, we address the use of nanotechnology in the fabrication of biomaterials (i.e., nanoparticles and nanofibers) and their therapeutic function in wound healing as dressing materials. Furthermore, we discuss the use of surface nanofeatures to regulate cell adhesion, migration, proliferation, and differentiation, which is a crucial step in wound healing associated with tissue regeneration. Given that nanotechnology-based biomaterials exhibit superior pharmaceutical performance as compared to the traditional medicine, this short review provides current status and future directions of how nanotechnology is and will be used in biomedical field, especially in wound healing.
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issn 1687-9503
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publishDate 2017-01-01
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series Journal of Nanotechnology
spelling doaj-art-3acfb387908c42eaabda8b9f4a7f36952025-02-03T05:54:41ZengWileyJournal of Nanotechnology1687-95031687-95112017-01-01201710.1155/2017/63417106341710A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound HealingShih-Feng Chou0Simi Gunaseelan1Mhd Hussam Hijazi Kiellani2Venkata Vamsi Krishna Thottempudi3Pierre Neuenschwander4Huarong Nie5Department of Mechanical Engineering, College of Engineering, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Pharmaceutical Sciences, Ben and Maytee Fisch College of Pharmacy, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Mechanical Engineering, College of Engineering, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Mechanical Engineering, College of Engineering, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX 75708, USAKey Laboratory of Rubber-Plastics, Ministry of Education, Qingdao University of Science and Technology, Qingdao 266042, ChinaThe two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as promote tissue regeneration. In this short review, we address the use of nanotechnology in the fabrication of biomaterials (i.e., nanoparticles and nanofibers) and their therapeutic function in wound healing as dressing materials. Furthermore, we discuss the use of surface nanofeatures to regulate cell adhesion, migration, proliferation, and differentiation, which is a crucial step in wound healing associated with tissue regeneration. Given that nanotechnology-based biomaterials exhibit superior pharmaceutical performance as compared to the traditional medicine, this short review provides current status and future directions of how nanotechnology is and will be used in biomedical field, especially in wound healing.http://dx.doi.org/10.1155/2017/6341710
spellingShingle Shih-Feng Chou
Simi Gunaseelan
Mhd Hussam Hijazi Kiellani
Venkata Vamsi Krishna Thottempudi
Pierre Neuenschwander
Huarong Nie
A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing
Journal of Nanotechnology
title A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing
title_full A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing
title_fullStr A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing
title_full_unstemmed A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing
title_short A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing
title_sort review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing
url http://dx.doi.org/10.1155/2017/6341710
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