A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing
The two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as prom...
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Format: | Article |
Language: | English |
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Wiley
2017-01-01
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Series: | Journal of Nanotechnology |
Online Access: | http://dx.doi.org/10.1155/2017/6341710 |
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author | Shih-Feng Chou Simi Gunaseelan Mhd Hussam Hijazi Kiellani Venkata Vamsi Krishna Thottempudi Pierre Neuenschwander Huarong Nie |
author_facet | Shih-Feng Chou Simi Gunaseelan Mhd Hussam Hijazi Kiellani Venkata Vamsi Krishna Thottempudi Pierre Neuenschwander Huarong Nie |
author_sort | Shih-Feng Chou |
collection | DOAJ |
description | The two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as promote tissue regeneration. In this short review, we address the use of nanotechnology in the fabrication of biomaterials (i.e., nanoparticles and nanofibers) and their therapeutic function in wound healing as dressing materials. Furthermore, we discuss the use of surface nanofeatures to regulate cell adhesion, migration, proliferation, and differentiation, which is a crucial step in wound healing associated with tissue regeneration. Given that nanotechnology-based biomaterials exhibit superior pharmaceutical performance as compared to the traditional medicine, this short review provides current status and future directions of how nanotechnology is and will be used in biomedical field, especially in wound healing. |
format | Article |
id | doaj-art-3acfb387908c42eaabda8b9f4a7f3695 |
institution | Kabale University |
issn | 1687-9503 1687-9511 |
language | English |
publishDate | 2017-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Nanotechnology |
spelling | doaj-art-3acfb387908c42eaabda8b9f4a7f36952025-02-03T05:54:41ZengWileyJournal of Nanotechnology1687-95031687-95112017-01-01201710.1155/2017/63417106341710A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound HealingShih-Feng Chou0Simi Gunaseelan1Mhd Hussam Hijazi Kiellani2Venkata Vamsi Krishna Thottempudi3Pierre Neuenschwander4Huarong Nie5Department of Mechanical Engineering, College of Engineering, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Pharmaceutical Sciences, Ben and Maytee Fisch College of Pharmacy, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Mechanical Engineering, College of Engineering, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Mechanical Engineering, College of Engineering, The University of Texas at Tyler, Tyler, TX 75799, USADepartment of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Tyler, TX 75708, USAKey Laboratory of Rubber-Plastics, Ministry of Education, Qingdao University of Science and Technology, Qingdao 266042, ChinaThe two major topics concerning the development of nanomedicine are drug delivery and tissue engineering. With the advance in nanotechnology, scientists and engineers now have the ability to fabricate functional drug carriers and/or biomaterials that deliver and release drugs locally as well as promote tissue regeneration. In this short review, we address the use of nanotechnology in the fabrication of biomaterials (i.e., nanoparticles and nanofibers) and their therapeutic function in wound healing as dressing materials. Furthermore, we discuss the use of surface nanofeatures to regulate cell adhesion, migration, proliferation, and differentiation, which is a crucial step in wound healing associated with tissue regeneration. Given that nanotechnology-based biomaterials exhibit superior pharmaceutical performance as compared to the traditional medicine, this short review provides current status and future directions of how nanotechnology is and will be used in biomedical field, especially in wound healing.http://dx.doi.org/10.1155/2017/6341710 |
spellingShingle | Shih-Feng Chou Simi Gunaseelan Mhd Hussam Hijazi Kiellani Venkata Vamsi Krishna Thottempudi Pierre Neuenschwander Huarong Nie A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing Journal of Nanotechnology |
title | A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing |
title_full | A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing |
title_fullStr | A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing |
title_full_unstemmed | A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing |
title_short | A Review of Injectable and Implantable Biomaterials for Treatment and Repair of Soft Tissues in Wound Healing |
title_sort | review of injectable and implantable biomaterials for treatment and repair of soft tissues in wound healing |
url | http://dx.doi.org/10.1155/2017/6341710 |
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