DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLC

A sensitive and developed the validation method for quantification by using the chromatograph for Etoricoxib. The method was validated in terms of specificity, linearity, accuracy, precision and analytical range. The results of validation method and approbation at selected sites are given. It was sh...

Full description

Saved in:
Bibliographic Details
Main Authors: T. L. Batalova, O. A. Ostapyuk, K. R. Saveleva, T. Y. Andreevicheva, L. V. Persanova, S. V. Polyakov, V. N. Shestakov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2019-01-01
Series:Разработка и регистрация лекарственных средств
Subjects:
Online Access:https://www.pharmjournal.ru/jour/article/view/551
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849243886059257856
author T. L. Batalova
O. A. Ostapyuk
K. R. Saveleva
T. Y. Andreevicheva
L. V. Persanova
S. V. Polyakov
V. N. Shestakov
author_facet T. L. Batalova
O. A. Ostapyuk
K. R. Saveleva
T. Y. Andreevicheva
L. V. Persanova
S. V. Polyakov
V. N. Shestakov
author_sort T. L. Batalova
collection DOAJ
description A sensitive and developed the validation method for quantification by using the chromatograph for Etoricoxib. The method was validated in terms of specificity, linearity, accuracy, precision and analytical range. The results of validation method and approbation at selected sites are given. It was shown than main validation characteristics meet the requirements. Using the HPLC method the dispersion was 0,253%. The analytical range of method is 25-85 µg/ml for HPLC.
format Article
id doaj-art-3acbcd43d1d04576b2c3542fb9b65264
institution Kabale University
issn 2305-2066
2658-5049
language Russian
publishDate 2019-01-01
publisher LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
record_format Article
series Разработка и регистрация лекарственных средств
spelling doaj-art-3acbcd43d1d04576b2c3542fb9b652642025-08-20T03:59:20ZrusLLC Center of Pharmaceutical Analytics (LLC «CPHA»)Разработка и регистрация лекарственных средств2305-20662658-50492019-01-01019095551DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLCT. L. Batalova0O. A. Ostapyuk1K. R. Saveleva2T. Y. Andreevicheva3L. V. Persanova4S. V. Polyakov5V. N. Shestakov6State Institute of Drugs and Good Practices, the Ministry of Industry and Trade of the Russian FederationState Institute of Drugs and Good Practices, the Ministry of Industry and Trade of the Russian FederationState Institute of Drugs and Good Practices, the Ministry of Industry and Trade of the Russian FederationState Institute of Drugs and Good Practices, the Ministry of Industry and Trade of the Russian FederationState Institute of Drugs and Good Practices, the Ministry of Industry and Trade of the Russian FederationState Institute of Drugs and Good Practices, the Ministry of Industry and Trade of the Russian FederationState Institute of Drugs and Good Practices, the Ministry of Industry and Trade of the Russian FederationA sensitive and developed the validation method for quantification by using the chromatograph for Etoricoxib. The method was validated in terms of specificity, linearity, accuracy, precision and analytical range. The results of validation method and approbation at selected sites are given. It was shown than main validation characteristics meet the requirements. Using the HPLC method the dispersion was 0,253%. The analytical range of method is 25-85 µg/ml for HPLC.https://www.pharmjournal.ru/jour/article/view/551validationetoricoxibhplc
spellingShingle T. L. Batalova
O. A. Ostapyuk
K. R. Saveleva
T. Y. Andreevicheva
L. V. Persanova
S. V. Polyakov
V. N. Shestakov
DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLC
Разработка и регистрация лекарственных средств
validation
etoricoxib
hplc
title DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLC
title_full DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLC
title_fullStr DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLC
title_full_unstemmed DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLC
title_short DEVELOPMENT AND VALIDATION THE METHOD OF QUANTITATIVE DETERMINATION OF ETORICOXIB IN SOLID PHARMACEUTICAL FORMS BY HPLC
title_sort development and validation the method of quantitative determination of etoricoxib in solid pharmaceutical forms by hplc
topic validation
etoricoxib
hplc
url https://www.pharmjournal.ru/jour/article/view/551
work_keys_str_mv AT tlbatalova developmentandvalidationthemethodofquantitativedeterminationofetoricoxibinsolidpharmaceuticalformsbyhplc
AT oaostapyuk developmentandvalidationthemethodofquantitativedeterminationofetoricoxibinsolidpharmaceuticalformsbyhplc
AT krsaveleva developmentandvalidationthemethodofquantitativedeterminationofetoricoxibinsolidpharmaceuticalformsbyhplc
AT tyandreevicheva developmentandvalidationthemethodofquantitativedeterminationofetoricoxibinsolidpharmaceuticalformsbyhplc
AT lvpersanova developmentandvalidationthemethodofquantitativedeterminationofetoricoxibinsolidpharmaceuticalformsbyhplc
AT svpolyakov developmentandvalidationthemethodofquantitativedeterminationofetoricoxibinsolidpharmaceuticalformsbyhplc
AT vnshestakov developmentandvalidationthemethodofquantitativedeterminationofetoricoxibinsolidpharmaceuticalformsbyhplc