The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical Trial

Background: Blood transfusion is a therapeutic procedure characterized by the use of blood components for the treatment of certain pathologies. When applied properly, it is highly successful; however, it also has risks, such as transfusion reactions. Objective: This study aimed to evaluate the effec...

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Main Authors: Ana Beatriz Frota Lima Rodrigues, Samia Valéria Ozorio Dutra, Maria Ivaneide Teixeira dos Santos, Lucas Ribeiro Araujo, Annie Leticia de Holanda Ferreira, Arthur Feitosa Jacinto, Brenda Sousa da Conceição, Gleiciane Kélen Lima, Igor Cordeiro Mendes, Elaine Cristina Negri, Maria Neyrian de Fátima Fernandes, Luciana Mara Monti Fonseca, Francisco Mayron Morais Soares
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Language:English
Published: MDPI AG 2025-06-01
Series:Education Sciences
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Online Access:https://www.mdpi.com/2227-7102/15/6/693
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author Ana Beatriz Frota Lima Rodrigues
Samia Valéria Ozorio Dutra
Maria Ivaneide Teixeira dos Santos
Lucas Ribeiro Araujo
Annie Leticia de Holanda Ferreira
Arthur Feitosa Jacinto
Brenda Sousa da Conceição
Gleiciane Kélen Lima
Igor Cordeiro Mendes
Elaine Cristina Negri
Maria Neyrian de Fátima Fernandes
Luciana Mara Monti Fonseca
Francisco Mayron Morais Soares
author_facet Ana Beatriz Frota Lima Rodrigues
Samia Valéria Ozorio Dutra
Maria Ivaneide Teixeira dos Santos
Lucas Ribeiro Araujo
Annie Leticia de Holanda Ferreira
Arthur Feitosa Jacinto
Brenda Sousa da Conceição
Gleiciane Kélen Lima
Igor Cordeiro Mendes
Elaine Cristina Negri
Maria Neyrian de Fátima Fernandes
Luciana Mara Monti Fonseca
Francisco Mayron Morais Soares
author_sort Ana Beatriz Frota Lima Rodrigues
collection DOAJ
description Background: Blood transfusion is a therapeutic procedure characterized by the use of blood components for the treatment of certain pathologies. When applied properly, it is highly successful; however, it also has risks, such as transfusion reactions. Objective: This study aimed to evaluate the effects of the clinical simulation of transfusion reactions on the knowledge gain of nursing students. Methods: Two groups were compared: the intervention group, which used the educational intervention: “clinical simulation of transfusion reactions in adults”, and the control group, which did not use the strategy. The study was conducted at a Higher Education Institution from August 2022 to June 2023, with nursing students in the fifth semester. An instrument on the knowledge of transfusion reactions was applied before and seven days after the intervention. Data were analyzed descriptively and inferentially using the Mann–Whitney U and Wilcoxon tests. For both, <i>p</i> < 0.05 was accepted. Results: The Wilcoxon test revealed a statistically significant difference in pre- and post-test scores within the intervention group (<i>p</i>-value: 0.003), with a large effect size (Cohen’s d = 1.14). The average score in the pre-test was 16.47 and increased to 18.93 in the post-test (<i>p</i> = 0.002), while in the control group there was a drop from 14.53 to 12.07 (<i>p</i> = 0.053). In terms of overall scores, the intervention group went from an average of 8.10 to 9.67 (<i>p</i> = 0.001), while the control group went from 8.13 to 8.66 (<i>p</i> = 0.053). The reduction in errors was significant in topics such as hand hygiene (from 56.7% to 23.3%) and the maximum exposure time of the blood component at room temperature (from 66.7% to 20%). The data showed that the clinical simulation intervention had a significant positive effect on the acquisition of theoretical knowledge about transfusion reactions. Conclusions: Through the use of simulation as a teaching strategy, students gained greater knowledge.
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spelling doaj-art-3abab46ea0d8454cb6d70c018239a99c2025-08-20T03:24:39ZengMDPI AGEducation Sciences2227-71022025-06-0115669310.3390/educsci15060693The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical TrialAna Beatriz Frota Lima Rodrigues0Samia Valéria Ozorio Dutra1Maria Ivaneide Teixeira dos Santos2Lucas Ribeiro Araujo3Annie Leticia de Holanda Ferreira4Arthur Feitosa Jacinto5Brenda Sousa da Conceição6Gleiciane Kélen Lima7Igor Cordeiro Mendes8Elaine Cristina Negri9Maria Neyrian de Fátima Fernandes10Luciana Mara Monti Fonseca11Francisco Mayron Morais Soares12Department of Nursing, Federal University of Maranhão, Imperatriz 65915-240, MA, BrazilSchool of Nursing and Dental Hygiene, University of Hawaii at Manoa, Honolulu, HI 96822, USAINTA Uninta University Center, Itapipoca 62600-000, CE, BrazilDepartment of Nursing, Federal University of Maranhão, Imperatriz 65915-240, MA, BrazilDepartment of Nursing, Federal University of Maranhão, Imperatriz 65915-240, MA, BrazilDepartment of Nursing, Federal University of Maranhão, Imperatriz 65915-240, MA, BrazilDepartment of Nursing, Federal University of Maranhão, Imperatriz 65915-240, MA, BrazilDepartment of Nursing, State University of Ceará, Fortaleza 60714-903, CE, BrazilDepartment of Nursing, State University of Ceará, Fortaleza 60714-903, CE, BrazilDepartment of Nursing, University of West Paulista, Presidente Prudente 19050-920, SP, BrazilDepartment of Nursing, Federal University of Maranhão, Imperatriz 65915-240, MA, BrazilEscola de Enfermagem de Ribeirão Preto, University of São Paulo, Ribeirão Preto 14040-902, SP, BrazilDepartment of Nursing, Federal University of Maranhão, Imperatriz 65915-240, MA, BrazilBackground: Blood transfusion is a therapeutic procedure characterized by the use of blood components for the treatment of certain pathologies. When applied properly, it is highly successful; however, it also has risks, such as transfusion reactions. Objective: This study aimed to evaluate the effects of the clinical simulation of transfusion reactions on the knowledge gain of nursing students. Methods: Two groups were compared: the intervention group, which used the educational intervention: “clinical simulation of transfusion reactions in adults”, and the control group, which did not use the strategy. The study was conducted at a Higher Education Institution from August 2022 to June 2023, with nursing students in the fifth semester. An instrument on the knowledge of transfusion reactions was applied before and seven days after the intervention. Data were analyzed descriptively and inferentially using the Mann–Whitney U and Wilcoxon tests. For both, <i>p</i> < 0.05 was accepted. Results: The Wilcoxon test revealed a statistically significant difference in pre- and post-test scores within the intervention group (<i>p</i>-value: 0.003), with a large effect size (Cohen’s d = 1.14). The average score in the pre-test was 16.47 and increased to 18.93 in the post-test (<i>p</i> = 0.002), while in the control group there was a drop from 14.53 to 12.07 (<i>p</i> = 0.053). In terms of overall scores, the intervention group went from an average of 8.10 to 9.67 (<i>p</i> = 0.001), while the control group went from 8.13 to 8.66 (<i>p</i> = 0.053). The reduction in errors was significant in topics such as hand hygiene (from 56.7% to 23.3%) and the maximum exposure time of the blood component at room temperature (from 66.7% to 20%). The data showed that the clinical simulation intervention had a significant positive effect on the acquisition of theoretical knowledge about transfusion reactions. Conclusions: Through the use of simulation as a teaching strategy, students gained greater knowledge.https://www.mdpi.com/2227-7102/15/6/693simulation trainingnursing caretransfusion reactionblood safetycompetency-based education
spellingShingle Ana Beatriz Frota Lima Rodrigues
Samia Valéria Ozorio Dutra
Maria Ivaneide Teixeira dos Santos
Lucas Ribeiro Araujo
Annie Leticia de Holanda Ferreira
Arthur Feitosa Jacinto
Brenda Sousa da Conceição
Gleiciane Kélen Lima
Igor Cordeiro Mendes
Elaine Cristina Negri
Maria Neyrian de Fátima Fernandes
Luciana Mara Monti Fonseca
Francisco Mayron Morais Soares
The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical Trial
Education Sciences
simulation training
nursing care
transfusion reaction
blood safety
competency-based education
title The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical Trial
title_full The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical Trial
title_fullStr The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical Trial
title_full_unstemmed The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical Trial
title_short The Effects of the Clinical Simulation of Transfusion Reactions on Nursing Students’ Knowledge Gain: A Pragmatic Clinical Trial
title_sort effects of the clinical simulation of transfusion reactions on nursing students knowledge gain a pragmatic clinical trial
topic simulation training
nursing care
transfusion reaction
blood safety
competency-based education
url https://www.mdpi.com/2227-7102/15/6/693
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