Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand

In this work, we present the design and synthesis of the <i>bis</i>thiosemicarbazone ligand H<sub>3</sub>L<sup>Me</sup> by means of an iminic condensation reaction between 2-hydroxyisophthalaldehyde and 4-methyl-3-thiosemicarbazide. This ligand is bicompartmental,...

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Main Authors: Isabel Velo-Heleno, Sandra Fernández-Fariña, Uxía Barreiro-Sisto, Laura Rodríguez-Silva, Rosa Pedrido
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Chemistry Proceedings
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Online Access:https://www.mdpi.com/2673-4583/14/1/39
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author Isabel Velo-Heleno
Sandra Fernández-Fariña
Uxía Barreiro-Sisto
Laura Rodríguez-Silva
Rosa Pedrido
author_facet Isabel Velo-Heleno
Sandra Fernández-Fariña
Uxía Barreiro-Sisto
Laura Rodríguez-Silva
Rosa Pedrido
author_sort Isabel Velo-Heleno
collection DOAJ
description In this work, we present the design and synthesis of the <i>bis</i>thiosemicarbazone ligand H<sub>3</sub>L<sup>Me</sup> by means of an iminic condensation reaction between 2-hydroxyisophthalaldehyde and 4-methyl-3-thiosemicarbazide. This ligand is bicompartmental, pentadentate [N<sub>2</sub>S<sub>2</sub>O] and potentially trianionic. The presence of a spacer constituted by a phenol group facilitates the coordination of transition metal ions, giving rise to a great variety of structures. To confirm the purity of the ligand, different characterization techniques were employed, including elemental analysis, mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance. The acquisition of suitable crystals of H<sub>3</sub>L<sup>Me</sup> allowed us to analyze its structure through X-ray diffraction studies.
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issn 2673-4583
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series Chemistry Proceedings
spelling doaj-art-3ab897eaee0b4748b8154151a14c68172025-08-20T02:00:39ZengMDPI AGChemistry Proceedings2673-45832023-11-011413910.3390/ecsoc-27-16093Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone LigandIsabel Velo-Heleno0Sandra Fernández-Fariña1Uxía Barreiro-Sisto2Laura Rodríguez-Silva3Rosa Pedrido4Suprabioin Lab, Departamento de Química Inorgánica, Facultade de Química, Universidade de Santiago de Compostela, Campus Vida, 15782 Santiago de Compostela, SpainSuprabioin Lab, Departamento de Química Inorgánica, Facultade de Química, Universidade de Santiago de Compostela, Campus Vida, 15782 Santiago de Compostela, SpainSuprabioin Lab, Departamento de Química Inorgánica, Facultade de Química, Universidade de Santiago de Compostela, Campus Vida, 15782 Santiago de Compostela, SpainSuprabioin Lab, Departamento de Química Inorgánica, Facultade de Ciencias, Universidade de Santiago de Compostela, Campus Terra, 27002 Lugo, SpainSuprabioin Lab, Departamento de Química Inorgánica, Facultade de Química, Universidade de Santiago de Compostela, Campus Vida, 15782 Santiago de Compostela, SpainIn this work, we present the design and synthesis of the <i>bis</i>thiosemicarbazone ligand H<sub>3</sub>L<sup>Me</sup> by means of an iminic condensation reaction between 2-hydroxyisophthalaldehyde and 4-methyl-3-thiosemicarbazide. This ligand is bicompartmental, pentadentate [N<sub>2</sub>S<sub>2</sub>O] and potentially trianionic. The presence of a spacer constituted by a phenol group facilitates the coordination of transition metal ions, giving rise to a great variety of structures. To confirm the purity of the ligand, different characterization techniques were employed, including elemental analysis, mass spectrometry, infrared spectroscopy, and nuclear magnetic resonance. The acquisition of suitable crystals of H<sub>3</sub>L<sup>Me</sup> allowed us to analyze its structure through X-ray diffraction studies.https://www.mdpi.com/2673-4583/14/1/39ligand<i>bis</i>thiosemicarbazonecoordination chemistry
spellingShingle Isabel Velo-Heleno
Sandra Fernández-Fariña
Uxía Barreiro-Sisto
Laura Rodríguez-Silva
Rosa Pedrido
Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand
Chemistry Proceedings
ligand
<i>bis</i>thiosemicarbazone
coordination chemistry
title Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand
title_full Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand
title_fullStr Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand
title_full_unstemmed Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand
title_short Design, Synthesis and Characterization of a Bicompartmental <i>bis</i>thiosemicarbazone Ligand
title_sort design synthesis and characterization of a bicompartmental i bis i thiosemicarbazone ligand
topic ligand
<i>bis</i>thiosemicarbazone
coordination chemistry
url https://www.mdpi.com/2673-4583/14/1/39
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