Unveiling the role of the PhoP master regulator in arsenite resistance through ackA downregulation in Lacticaseibacillus paracasei

Unveiling the role of the PhoP master regulator in arsenite resistance through ackA downregulation in Lacticaseibacillus paracasei

In bacteria, the two-component system PhoPR plays an important role in regulating many genes related to phosphate uptake and metabolism. In Lacticaseibacillus paracasei inactivation of the response regulator PhoP results in increased resistance to arsenite [As(III)]. A comparative transcriptomic ana...

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Bibliographic Details
Main Authors: Daniela Corrales, Cristina Alcántara, Dinoraz Vélez, Vicenta Devesa, Vicente Monedero, Manuel Zúñiga
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Microbial Sciences
Subjects:
Lacticaseibacillus paracasei
Arsenite
Phosphate
Acetate kinase
Pho regulon
Online Access:http://www.sciencedirect.com/science/article/pii/S2666517425000197
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