Evaluating perineural invasion severity in head and neck cutaneous squamous cell carcinomas to refine prognostic accuracy: A retrospective case-control study

Evaluating perineural invasion severity in head and neck cutaneous squamous cell carcinomas to refine prognostic accuracy: A retrospective case-control study

Aims: Perineural invasion (PNI) is a well-recognized risk factor for head and neck cutaneous squamous cell carcinoma (HNCSCC). This study investigates whether a detailed scoring system for PNI can improve prognostic accuracy in HNCSCC, beyond the traditional PNI binary assessment. Methods: Among the...

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Main Authors: Filippo Nozzoli, Silvia Mancini, Andrea Ambrosini-Spaltro, Emilia Crisanti, Luca Riccioni, Giovanni De Luca, Annarita Lombardi, Fabio Falcini, Rosa Vattiato, Federica Zamagni, Lorenzo Borgognoni, Serena Sestini, Vincenzo De Giorgi, Laura Doni, Ismaela Vascotto, Angelo Cassisa, Chiara Anichini, Romina Nassini, Pierangelo Geppetti, Emanuele Crocetti, Ignazio Stanganelli, Daniela Massi
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:EJC Skin Cancer
Subjects:
Perineural invasion
PNI scoring system
Head and neck
Cutaneous squamous cell carcinoma
Disease free survival
Disease-specific survival
Online Access:http://www.sciencedirect.com/science/article/pii/S2772611825004641
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