Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry
Curcumin compounds are important bioactive compounds in ginger, yet their analysis is limited by their low concentrations. In the current research, a highly sensitive and reliable approach for simultaneous quantitative detection of three curcumin compounds in ginger samples was established using ult...
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| Format: | Article |
| Language: | English |
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Maximum Academic Press
2024-10-01
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| Series: | Food Innovation and Advances |
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| Online Access: | https://www.maxapress.com/article/doi/10.48130/fia-0024-0033 |
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| author | Yixuan Jiang Xiuhua Liu Yinfeng Zhao Jiguang Zhang Jing Qiu Yongzhong Qian Rui Weng |
| author_facet | Yixuan Jiang Xiuhua Liu Yinfeng Zhao Jiguang Zhang Jing Qiu Yongzhong Qian Rui Weng |
| author_sort | Yixuan Jiang |
| collection | DOAJ |
| description | Curcumin compounds are important bioactive compounds in ginger, yet their analysis is limited by their low concentrations. In the current research, a highly sensitive and reliable approach for simultaneous quantitative detection of three curcumin compounds in ginger samples was established using ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS). The extraction solvent, volume of extraction solvent, sonication time, and oscillation time were optimized by a single factor experiment. The method validation results showed that the regression coefficients were higher than 0.9990, and the linearity was satisfactory. Matrix effects were negligible with the values of 94.6%–98.8%. The recovery at three spiking levels was between 81.7% and 100.0%, and the precision was less than 5.4%. The approach could be used to determine the curcumin components in ginger samples since the results demonstrate that it is easy to use, practicable, repeatable, and accurate. |
| format | Article |
| id | doaj-art-3aa1e9ecd5a14b8aaab2e0fd31f398d7 |
| institution | OA Journals |
| issn | 2836-774X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Maximum Academic Press |
| record_format | Article |
| series | Food Innovation and Advances |
| spelling | doaj-art-3aa1e9ecd5a14b8aaab2e0fd31f398d72025-08-20T02:12:31ZengMaximum Academic PressFood Innovation and Advances2836-774X2024-10-013435335910.48130/fia-0024-0033fia-0024-0033Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometryYixuan Jiang0Xiuhua Liu1Yinfeng Zhao2Jiguang Zhang3Jing Qiu4Yongzhong Qian5Rui Weng6Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture and Rural Affairs, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture and Rural Affairs, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture and Rural Affairs, Beijing 100081, ChinaTobacco Research Institute, Chinese Academy of Agricultural Sciences, Laboratory of Risk Assessment for Tobacco Quality and Safety (Qingdao), Ministry of Agriculture and Rural Affairs, Qingdao 266101, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture and Rural Affairs, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture and Rural Affairs, Beijing 100081, ChinaInstitute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agri-food Quality and Safety, Ministry of Agriculture and Rural Affairs, Beijing 100081, ChinaCurcumin compounds are important bioactive compounds in ginger, yet their analysis is limited by their low concentrations. In the current research, a highly sensitive and reliable approach for simultaneous quantitative detection of three curcumin compounds in ginger samples was established using ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS). The extraction solvent, volume of extraction solvent, sonication time, and oscillation time were optimized by a single factor experiment. The method validation results showed that the regression coefficients were higher than 0.9990, and the linearity was satisfactory. Matrix effects were negligible with the values of 94.6%–98.8%. The recovery at three spiking levels was between 81.7% and 100.0%, and the precision was less than 5.4%. The approach could be used to determine the curcumin components in ginger samples since the results demonstrate that it is easy to use, practicable, repeatable, and accurate.https://www.maxapress.com/article/doi/10.48130/fia-0024-0033curcumindemethoxycurcuminbisdemethoxycurcuminuhplc-ms/msginger |
| spellingShingle | Yixuan Jiang Xiuhua Liu Yinfeng Zhao Jiguang Zhang Jing Qiu Yongzhong Qian Rui Weng Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry Food Innovation and Advances curcumin demethoxycurcumin bisdemethoxycurcumin uhplc-ms/ms ginger |
| title | Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry |
| title_full | Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry |
| title_fullStr | Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry |
| title_full_unstemmed | Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry |
| title_short | Quantitative analysis of curcumin compounds in ginger by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry |
| title_sort | quantitative analysis of curcumin compounds in ginger by ultra high performance liquid chromatography coupled with tandem mass spectrometry |
| topic | curcumin demethoxycurcumin bisdemethoxycurcumin uhplc-ms/ms ginger |
| url | https://www.maxapress.com/article/doi/10.48130/fia-0024-0033 |
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